EED 抗体 (N-Term)
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- 抗原 See all EED 抗体
- EED (Embryonic Ectoderm Development (EED))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EED antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AKKQKLSSDE NSNPDLSGDE NDDAVSIESG TNTERPDTPT NTPNAPGRKS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against Eed. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product EED Primary Antibody
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anti-Embryonic Ectoderm Development (EED) (N-Term) antibody
EED 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 马, 兔 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 1-100) antibodyEED 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 342-441) antibodyEED 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B12 unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 142-441) antibodyEED 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 1-300) antibodyEED 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 269-303) antibodyEED 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB51180 unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 21-70) antibodyEED 适用: 人, 小鼠, 大鼠, 非洲爪蟾, 犬, Cow, 斑马鱼, 豚鼠, 马, 兔, Bat, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 1-441) antibodyEED 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 1-300) antibodyEED 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 40-74), (N-Term) antibodyEED 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51500 unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 441 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- EED (Embryonic Ectoderm Development (EED))
- 别名
- Eed (EED 产品)
- 别名
- Xeed antibody, heed antibody, wait1 antibody, EED antibody, HEED antibody, WAIT1 antibody, zgc:112509 antibody, Xeed-B antibody, eed antibody, psXEED antibody, ENSMUSG00000039373 antibody, l(7)5Rn antibody, l7Rn5 antibody, lusk antibody, Xeed-A antibody, embryonic ectoderm development antibody, embryonic ectoderm development S homeolog antibody, microRNA 6755 antibody, embryonic ectoderm development L homeolog antibody, eed antibody, EED antibody, eed.S antibody, MIR6755 antibody, Eed antibody, eed.L antibody
- 背景
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Eed is a polycomb group (PcG) protein. It is a component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXA7, HOXB6 and HOXC8. Eed plays a role in X chromosome inactivation (XCI), in which one of the two X chromosomes in female mammals is transcriptionally silenced to equalize X-linked gene dosage with XY males. Eed is required for stable maintenance of XCI in both embryonic and extra-embryonic tissues. Eed may prevent transcriptional activation of facultative heterochromatin during differentiation. Eed is required for development of secondary trophoblast giant cells during placental development. Eed may regulate hippocampal synaptic plasticity in the developing brain.
Alias Symbols: ENSMUSG00000039373, l(7)5Rn, l7Rn5, lusk
Protein Interaction Partner: Ezh2, Suz12, Rab3gap1, Ddx47, Nop10, Nip7, Bola2, Tmem14c, Uqcr10, Eif3f, Cbwd1, Smc5, Etf1, Svil, Fbxo11, Srsf7, Safb, Safb2, Abcf1, Bag6, C330027C09Rik, Pak2, Pphln1, Ttll12, Sun2, Tomm22, Eif3l, E430025E21Rik, Eny2, Dcaf13, Trio, Ccar2, Fermt2, Vps41,
Protein Size: 441 - 分子量
- 50 kDa
- 基因ID
- 13626
- NCBI登录号
- NM_021876, NP_068676
- UniProt
- Q921E6
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