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VDAC1 抗体 (C-Term)

VDAC1 适用: 人, 大鼠, 小鼠, 兔, Cow, 犬, 豚鼠, 马, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776153
发货至: 中国
  • 抗原 See all VDAC1 抗体
    VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))
    抗原表位
    • 15
    • 12
    • 7
    • 7
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 90
    • 46
    • 35
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 兔, Cow, 犬, 豚鼠, 马, 绵羊, 斑马鱼
    宿主
    • 74
    • 24
    克隆类型
    • 64
    • 34
    多克隆
    标记
    • 45
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VDAC1 antibody is un-conjugated
    应用范围
    • 77
    • 42
    • 35
    • 19
    • 18
    • 13
    • 13
    • 10
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    SAKVNNSSLI GLGYTQTLKP GIKLTLSALL DGKNVNAGGH KLGLGLEFQA
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against VDAC1. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human VDAC1
    Top Product
    Discover our top product VDAC1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 283 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Rousset, Nguyen, Grange, Morel, Lardy: "Heme oxygenase-1 regulates matrix metalloproteinase MMP-1 secretion and chondrocyte cell death via Nox4 NADPH oxidase activity in chondrocytes." in: PLoS ONE, Vol. 8, Issue 6, pp. e66478, (2013) (PubMed).

    Arduíno, Esteves, Cortes, Silva, Patel, Grazina, Swerdlow, Oliveira, Cardoso: "Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic." in: Human molecular genetics, Vol. 21, Issue 21, pp. 4680-702, (2012) (PubMed).

    Chen, Martin, Maya-Mendoza, Tang, Lovri?, Sims, Jackson: "Reduced expression of lamin A/C results in modified cell signaling and metabolism coupled with changes in expression of structural proteins." in: Journal of proteome research, Vol. 8, Issue 11, pp. 5196-211, (2009) (PubMed).

  • 抗原
    VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))
    别名
    VDAC1 (VDAC1 产品)
    别名
    vdac1 antibody, VDAC1 antibody, 5076 antibody, ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 1 antibody, ATVDAC1 antibody, T22N4.9 antibody, T22N4_9 antibody, voltage dependent anion channel 1 antibody, PORIN antibody, VDAC-1 antibody, AL033343 antibody, Vdac5 antibody, fa13f11 antibody, wu:fa13f11 antibody, zgc:85830 antibody, voltage-dependent anion channel 1 S homeolog antibody, voltage-dependent anion channel 1 antibody, voltage dependent anion channel 1 antibody, vdac1.S antibody, vdac1 antibody, VDAC1 antibody, Vdac1 antibody
    背景
    The voltage-dependent anion-selective channel 1 (VDAC1) functions as a channel in membranous structures for the outer mitochondrial membrane, the cell membrane, endosomes, caveolae, the sarcoplasmatic reticulum, synaptosomes, and post-synaptic density fraction. A major function of VDAC1 in the plasma membrane is that of a NADH(-ferricyanide) reductase that may be involved in the maintenance of cellular redox homeostasis.
    Alias Symbols: PORIN, VDAC-1
    Protein Interaction Partner: UBC, KLHL40, SPRTN, MDM2, ADRB2, ASB14, ASB17, PARK2, BAG3, env, VCAM1, HK1, ATF2, FMNL1, TUBA1B, MDC1, CAV1, Htt, SFXN3, SUGP1, UBAP2, UFM1, ACAD9, MGAT4B, ACAA2, ZMPSTE24, VAPA, ALDH5A1, SF1, VDAC3, VDAC2, UBA52, TIAL1, FLOT2, CDK2, SIRT7, SUMO4, MAPK3,
    Protein Size: 283
    分子量
    31 kDa
    基因ID
    7416
    NCBI登录号
    NM_003374, NP_003365
    UniProt
    Q5FVE7
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