NFKBIB 抗体 (Middle Region)
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- 抗原 See all NFKBIB 抗体
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NFKBIB antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PILARLLRAH GAPEPEGEDE KSGPCSSSSD SDSGDEGDEY DDIVVHSSRS
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 91%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against NFKBIB. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NFKBIB
- Top Product
- Discover our top product NFKBIB Primary Antibody
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anti-NF-kappa-B inhibitor beta (NFKBIB) (pSer23) antibody
NFKBIB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) antibodyNFKBIB 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 1-356) antibodyNFKBIB 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 1-356) antibodyNFKBIB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) antibodyNFKBIB 适用: 人, 小鼠, 大鼠 IHC (p), IF 宿主: 小鼠 Monoclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 56-145) antibodyNFKBIB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 56-237) antibodyNFKBIB 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (N-Term) antibodyNFKBIB 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (C-Term) antibodyNFKBIB 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) antibodyNFKBIB 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 356 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
- 别名
- NFKBIB (NFKBIB 产品)
- 背景
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Inhibition of NFkappa-B activity by the hepatitis C virus core protein might be related to its physical interaction with and interrupted nuclear localization of IKKbeta. Increased nuclear factor-kappaB (NF-kB) activity in the amnion during labor is associated with an increase in the expression of NF-kBp65 and of the NF-kB binding proteins IkBa, IkBb-1 and IkBb-2. IkappaBbeta may be a novel target for transcription factors of the HMG-box SRY/Sox family and imply a potential role for NF-kappaB/IkappaBbeta in spermatogenesis. NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-766 BM449613.1 1-766 767-1189 BU634404.1 18-440 c 1190-1198 AI684894.1 1-9 c
Alias Symbols: IKBB, TRIP9
Protein Interaction Partner: VPS52, UBC, BAG3, TSPAN1, GIT2, RELA, REL, CSNK2A1, CDC25A, BAK1, APP, ZBTB7A, DNAJA3, IKBKB, CHUK, BRAP, IKBKG, TRE17, NFKBIA, NCOR2, PPARG, ESR2, POLR1D, POLR1E, POLR1A, POLR1C, POLR2H, NKIRAS2, POLR1B, NKIRAS1, LRPPRC, RASAL2, MTIF2, BTRC, CUL1, SKP1,
Protein Size: 356 - 分子量
- 38 kDa
- 基因ID
- 4793
- NCBI登录号
- NM_002503, NP_002494
- UniProt
- Q15653
- 途径
- NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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