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MARCH2 抗体 (Middle Region)

MARCH2 适用: 人, 大鼠, 小鼠, 豚鼠, 兔, 犬, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775654
发货至: 中国
  • 抗原 See all MARCH2 抗体
    MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))
    抗原表位
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 大鼠, 小鼠, 豚鼠, 兔, 犬, Cow, 马
    宿主
    • 29
    • 4
    • 1
    克隆类型
    • 33
    • 1
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MARCH2 antibody is un-conjugated
    应用范围
    • 30
    • 13
    • 8
    • 6
    • 5
    • 4
    • 1
    Western Blotting (WB)
    序列
    LFITPLAAIS GWLCLRGAQD HLRLHSQLEA VGLIALTIAL FTIYVLWTLV
    预测反应
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against MARCH2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human MARCH2
    Top Product
    Discover our top product MARCH2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 246 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wakisaka, Tsuda, Yamada, Yagihara, Kitamura: "Long-term results of saphenous vein graft for coronary stenosis caused by Kawasaki disease." in: Circulation journal : official journal of the Japanese Circulation Society, Vol. 73, Issue 1, pp. 73-7, (2008) (PubMed).

  • 抗原
    MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))
    别名
    MARCH2 (MARCH2 产品)
    别名
    MARCH-II antibody, RNF172 antibody, rgd1306395 antibody, marh2 antibody, RGD1306395 antibody, 9530046H09Rik antibody, membrane associated ring-CH-type finger 2 antibody, membrane associated ring-CH-type finger 2 S homeolog antibody, E3 ubiquitin-protein ligase MARCH2 antibody, membrane-associated ring finger (C3HC4) 2 antibody, MARCH2 antibody, march2.S antibody, march2 antibody, Tsp_09446 antibody, marh2 antibody, March2 antibody
    背景
    MARCH2 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. MARCH2 may be involved in endosomal trafficking through interaction with STX6.
    Alias Symbols: HSPC240, MARCH-II, RNF172
    Protein Interaction Partner: LDLRAD1, SYNE4, CCDC155, FATE1, UBE2H, UBE2D1, CDC34, GOPC, STX6, CFTR, ADRB2, ELAVL1, DLG1,
    Protein Size: 246
    分子量
    27 kDa
    基因ID
    51257
    NCBI登录号
    NM_001005415, NP_001005415
    UniProt
    Q9P0N8
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