我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

PKC zeta 抗体 (N-Term)

Name: PKC zeta 抗体 (N-Term)
SKU: ABIN2775614
Availability: OutOfStock

This anti-PKC zeta antibody is a 兔多克隆 antibody detecting PKC zeta in WB. Suitable for 人, 小鼠, 大鼠, 兔, Cow, 犬, 马和豚鼠.

WB Suggested Anti-PRKCZ Antibody Titration: 0. (PKC zeta 抗体 (N-Term))

Rabbit Anti-PRKCZ Antibody Formalin Fixed Paraffin Embedded Tissue: Human Testis Tissue Observed Staining: Cytoplasm Primary Antibody Concentration: 1:600 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0. (PKC zeta 抗体 (N-Term))

IHC

2 images

产品编号 ABIN2775614

发货至: 中国

Datasheet as PDF

Quick Overview for PKC zeta 抗体 (N-Term) (ABIN2775614)

抗原

See all PKC zeta (PRKCZ) 抗体

PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

适用

人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This PKC zeta antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product PRKCZ Primary Antibody

抗原表位
30

28

8

8

6

5

5

4

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term

序列

MDSVMPSQEP PVDDKNEDAD LPSEETDGIA YISSSRKHDS IKDDSEDLKP

预测反应

Cow: 77%, Dog: 75%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 92%, Rabbit: 79%, Rat: 92%

产品特性

This is a rabbit polyclonal antibody against PRKCZ. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human PRKCZ
anti-Protein Kinase C, zeta (PRKCZ) (C-Term) antibody
PRKCZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (pThr410) antibody
PRKCZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (AA 165-255) antibody
PRKCZ 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2D1 unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (AA 453-592) antibody
PRKCZ 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (Cytoplasmic Domain) antibody
PRKCZ 适用: 人 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (pThr560) antibody
PRKCZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, zeta (PRKCZ) antibody
PRKCZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 兔 Monoclonal R14-K unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (N-Term) antibody
PRKCZ 适用: 人 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (Thr33) antibody
PRKCZ 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Kinase C, zeta (PRKCZ) (pThr410) antibody
PRKCZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 409 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

别名

PRKCZ

背景

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC.Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: PKC2, PKC-ZETA
Protein Interaction Partner: MAPK7, PRKCZ, AKT2, AKT1, Sqstm1, PARD6A, NUMB, NPM1, HIST1H1B, CFL1, C1QBP, HSP90AA1, NCF1, MARCKS, PPP1R14A, HIST1H1A, UBC, VHL, LRRK2, AJUBA, PARD6B, PAWR, Smurf1, Smurf2, Pard3, HIST3H3, CD44, NCOA3, TFF1, RELA, ESR1, MBP, TRIM41, PIAS4, CCDC115, ZNF7
Protein Size: 409

分子量

45 kDa

基因ID

5590

NCBI登录号

NM_001033581, NP_001028753

UniProt

Q05513

途径

NF-kappaB Signaling, RTK signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling