Axin 抗体 (N-Term)
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北京 101111
Quick Overview for Axin 抗体 (N-Term) (ABIN2775612)
抗原
See all Axin (AXIN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Axin1 Antibody - N-terminal region
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序列
- TVGRDQALGA RQAERPWPPH SHPSTPEPSV RNDGKRRFMG VRRQGSRGAG
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产品特性
- This is a rabbit polyclonal antibody against Axin1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Axin1
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anti-Axin 1 (AXIN1) (AA 546-752) antibody
AXIN1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E9F1 unconjugated
anti-Axin 1 (AXIN1) (AA 618-827) antibodyAXIN1 适用: 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 643-740) antibodyAXIN1 适用: 人 ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Axin 1 (AXIN1) (AA 546-752) antibodyAXIN1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4F10G1 unconjugated
anti-Axin 1 (AXIN1) (AA 710-738), (C-Term) antibodyAXIN1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31751 unconjugated
anti-Axin 1 (AXIN1) (AA 653-862) antibodyAXIN1 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 761-862) antibodyAXIN1 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 710-738) antibodyAXIN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 654-863) antibodyAXIN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Axin 1 (AXIN1) (C-Term) antibodyVerified AXIN1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42875-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Axin (AXIN1) (Axin 1 (AXIN1))
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别名
- Axin1
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背景
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Background Information: Axin1 is a component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Axin1 controls dorsoventral patterning via two opposing effects, down-regulates beta-catenin to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. It also facilitates the phosphorylation of APC by GSK3B, facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation and enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting the degradation of inhibitory SMAD7.
Alternative Symbols: Fu, Kb, Ki, Axin, fused, kinky, knobbly, AI316800
Protein Name: Axin-1
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分子量
- 110kDa
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基因ID
- 12005
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NCBI登录号
- XP_920000
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UniProt
- O70239
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途径
- WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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