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C-Type Lectin Domain Family 4, Member M (CLEC4M) (N-Term) 抗体

CLEC4M 适用: 人, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775393
发货至: 中国
  • 抗原 See all C-Type Lectin Domain Family 4, Member M (CLEC4M) 抗体
    C-Type Lectin Domain Family 4, Member M (CLEC4M)
    抗原表位
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 32
    • 10
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    人, Pig
    宿主
    • 27
    • 5
    克隆类型
    • 25
    • 6
    • 1
    多克隆
    标记
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 17
    • 10
    • 9
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    LVLQLLSFML LAGVLVAILV QVSKVPSSLS QEQSEQDAIY QNLTQLKAAV
    预测反应
    Human: 100%, Pig: 86%
    产品特性
    This is a rabbit polyclonal antibody against CLEC4M. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human CLEC4M
    Top Product
    Discover our top product CLEC4M Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 399 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    C-Type Lectin Domain Family 4, Member M (CLEC4M)
    别名
    CLEC4M (CLEC4M 产品)
    别名
    CD209L antibody, CD299 antibody, DC-SIGN2 antibody, DC-SIGNR antibody, DCSIGNR antibody, HP10347 antibody, L-SIGN antibody, LSIGN antibody, CD209B antibody, C-type lectin domain family 4 member M antibody, CLEC4M antibody
    背景
    CLEC4M is a type II integral membrane protein that is 77 % identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a type II integral membrane protein that is 77 % identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
    Alias Symbols: CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, L-SIGN, LSIGN, MGC129964, MGC47866
    Protein Interaction Partner: TLR2, MME, CLEC4M, CD209, ICAM3, ITGAM, AP2M1, HCVgp1,
    Protein Size: 399
    分子量
    44 kDa
    基因ID
    10332
    NCBI登录号
    NM_014257, NP_055072
    UniProt
    Q9H2X3
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