MARCH1 抗体 (N-Term)
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- 抗原 See all MARCH1 抗体
- MARCH1 (Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 马, 兔, 豚鼠, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MARCH1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LQASSPTTGT APRSQSRLSV CPSTQDICRI CHCEGDEESP LITPCRCTGT
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MARCH1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MARCH1
- Top Product
- Discover our top product MARCH1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 272 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MARCH1 (Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1))
- 别名
- MARCH1 (MARCH1 产品)
- 别名
- MARCH-I antibody, RNF171 antibody, 2900024D24Rik antibody, BB085186 antibody, RGD1305148 antibody, MARCH1 antibody, DKFZp459K1250 antibody, membrane associated ring-CH-type finger 1 antibody, membrane-associated ring finger (C3HC4) 1 antibody, MARCH1 antibody, March1 antibody
- 背景
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MARCH1 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC, CD86 and FAS, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Alias Symbols: DKFZp564M1682, FLJ20668, MARCH-I, RNF171
Protein Interaction Partner: TNFRSF10A, UBE2H, UBE2D1, CDC34, TFRC, UBC, HLA-DRB1, HLA-DRA, PPP2R1B, PPP2R1A, CD86,
Protein Size: 272 - 分子量
- 31 kDa
- 基因ID
- 55016
- NCBI登录号
- NM_017923, NP_060393
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