Migration-inducing gene 15 protein, MLD, dihydroceramide desaturase, sphingolipid delta 4 desaturase, DES1, MGC5079, DEGS,The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.
纯化方法
Antigen Immunoaffiinity Purification
免疫原
Synthetic peptide derived from the human DEGS1 protein
亚型
IgG
应用备注
Antibody can be used for Western blotting (1:400 starting dilution) and immunohistochemistry (10-15 μg/mL). Optimal concentration should be evaluated by serial dilutions.
限制
仅限研究用
浓度
Lot specific
缓冲液
Provided as solution in Tris buffered saline with 0.08 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles