Cysteine String Protein (CSP) alpha 抗体
适用: 人
ELISA, WB
宿主: 兔
Polyclonal
unconjugated
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- 抗原
- Cysteine String Protein (CSP) alpha
- 适用
- 人
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- ELISA, Western Blotting (WB)
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- CSP, DnaJ homolog subfamily C member 5,May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings. The amino terminus of CSP contains the J domain, a consensus sequence found on a DnaJ like protein which is a member of the heatshock protein family. Since heat shock proteins serve as chaperones that participate in protein folding and protein complex formation, CSP is believed to perform similar functions in the assembly of synaptic vesicle proteins which are essential to membrane trafficking. Evidence for a role of CSP in presynaptic neurotransmitter release has come from genetic and physiological study in which the Drosophila CSP null mutant fails to elicit synaptic potential upon high frequency stimulation. CSP null mutants have a lethal phenotype and for the small percentage of mutant flies that survive, they become paralyzed and die at elevated temperature.
- 纯化方法
- Ammonium Sulfate Precipitation
- 免疫原
- Synthetic peptide derived from the human CSP protein.
- 亚型
- IgG
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- 应用备注
- Antibody can be used for immunohistochemistry (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
- 限制
- 仅限研究用
-
- 缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- 抗原
- Cysteine String Protein (CSP) alpha
- UniProt
- Q9H3Z4
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