hCoV-OC43 Spike 抗体 (AA 15-344) (FITC)
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- 抗原 See all hCoV-OC43 Spike (HCoV-OC43 S) products
- hCoV-OC43 Spike (HCoV-OC43 S) (Coronavirus OC43 Spike Protein (HCoV-OC43 S))
- 抗原表位
- AA 15-344
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适用
- Human Coronavirus OC43 (HCoV-OC43)
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This hCoV-OC43 Spike antibody is conjugated to FITC
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应用范围
- ELISA
- 纯化方法
- Caprylic Acid Ammonium Sulfate Precipitation
- 免疫原
- Recombinant Human coronavirus OC43 Spike glycoprotein protein(15-344aa)
- 亚型
- IgG
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C/-80 °C
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- 抗原
- hCoV-OC43 Spike (HCoV-OC43 S) (Coronavirus OC43 Spike Protein (HCoV-OC43 S))
- 别名
- OC43 Spike Glycoprotein (HCoV-OC43 S 产品)
- 物质类
- Viral Protein
- 背景
- S1 attaches the virion to the cell membrane by interacting with sialic acid-containing cell receptors, initiating the infection. S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
- UniProt
- P36334
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