Thyroglobulin 抗体
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- 抗原 See all Thyroglobulin (TG) 抗体
- Thyroglobulin (TG)
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Thyroglobulin antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- Human TG / Thyroglobulin
- 纯化方法
- Protein G purified
- 免疫原
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Human thyroid follicular cells were used as the immunogen for this Thyroglobulin antibody.
Type of Immunogen: Cells - 克隆位点
- 6E1 or TGB05
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TG Primary Antibody
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- 应用备注
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Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IHC, IHC-P (0.5 - 1 μg/mL), WB (0.5 - 1 μg/mL)
Usage: Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites, detected at ~300 kDa in western blot. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for thyroglobulin antibody even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently thyroglobulin antibody negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Thyroglobulin antibody, combined with calcitonin antibody, can identify medullary carcinomas of the thyroid. Furthermore, thyroglobulin antibody, combined with TTF1 antibody, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. ELISA: Order BSA-free format for coating. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2°C to 8°C.
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- 抗原
- Thyroglobulin (TG)
- 别名
- TG / Thyroglobulin (TG 产品)
- 别名
- TG antibody, cb717 antibody, AITD3 antibody, TGN antibody, Tgn antibody, cog antibody, thyroglobulin antibody, TG antibody, tg antibody, LOC701526 antibody, LOC701756 antibody, LOC100434297 antibody, Tg antibody
- 背景
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Name/Gene ID: TG
Synonyms: TG, AITD3, TDH3, Thyroglobulin, TGN - 基因ID
- 7038
- 途径
- Thyroid Hormone Synthesis
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