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Thyroglobulin 抗体

TG 适用: 人, 小鼠, 大鼠 IHC, FACS, ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 6E1 or TGB05 unconjugated
产品编号 ABIN2744777
发货至: 中国
  • 抗原 See all Thyroglobulin (TG) 抗体
    Thyroglobulin (TG)
    适用
    • 95
    • 36
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    人, 小鼠, 大鼠
    宿主
    • 55
    • 39
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    小鼠
    克隆类型
    • 59
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    单克隆
    标记
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    This Thyroglobulin antibody is un-conjugated
    应用范围
    • 37
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    Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Human TG / Thyroglobulin
    纯化方法
    Protein G purified
    免疫原
    Human thyroid follicular cells were used as the immunogen for this Thyroglobulin antibody.

    Type of Immunogen: Cells
    克隆位点
    6E1 or TGB05
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TG Primary Antibody
  • 应用备注
    Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IHC, IHC-P (0.5 - 1 μg/mL), WB (0.5 - 1 μg/mL)

    Usage: Thyroglobulin is a 660  kDa dimeric pre-protein with mutiple glycosylation sites, detected at ~300  kDa in western blot. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for thyroglobulin antibody even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently thyroglobulin antibody negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Thyroglobulin antibody, combined with calcitonin antibody, can identify medullary carcinomas of the thyroid. Furthermore, thyroglobulin antibody, combined with TTF1 antibody, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. ELISA: Order BSA-free format for coating.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2°C to 8°C.
  • 抗原
    Thyroglobulin (TG)
    别名
    TG / Thyroglobulin (TG 产品)
    别名
    TG antibody, cb717 antibody, AITD3 antibody, TGN antibody, Tgn antibody, cog antibody, thyroglobulin antibody, TG antibody, tg antibody, LOC701526 antibody, LOC701756 antibody, LOC100434297 antibody, Tg antibody
    背景
    Name/Gene ID: TG

    Synonyms: TG, AITD3, TDH3, Thyroglobulin, TGN
    基因ID
    7038
    途径
    Thyroid Hormone Synthesis
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