Integrin beta 4 抗体
-
- 抗原 See all Integrin beta 4 (ITGB4) 抗体
- Integrin beta 4 (ITGB4)
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Integrin beta 4 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Reagent (BR)
- 特异性
- Human ITGB4 / Integrin Beta 4
- 纯化方法
- Protein G purified
- 免疫原
-
The human squamous cell carcinoma line (UM-SCC1).
Type of Immunogen: Cells - 克隆位点
- UM-A9
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product ITGB4 Primary Antibody
-
-
- 应用备注
-
Approved: Block, Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL)
Usage: This antibody recognizes a protein of 205 kDa, which is identified as integrin beta 4 (ITGB4) and CD104. Its epitope is localized in the extracellular domain of integrin beta 4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. ELISA: Order BSA-free format for coating. - 说明
-
Target Species of Antibody: Human
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2°C to 8°C.
-
- 抗原
- Integrin beta 4 (ITGB4)
- 别名
- ITGB4 / Integrin beta 4 (ITGB4 产品)
- 别名
- AA407042 antibody, C230078O20 antibody, CD104 antibody, integrin subunit beta 4 antibody, integrin beta 4 antibody, ITGB4 antibody, Itgb4 antibody
- 背景
-
Name/Gene ID: ITGB4
Family: Integrin
Synonyms: ITGB4, CD104, Integrin beta-4, Integrin Beta 4, gp150, CD104 antigen, Integrin beta-4 subunit, Integrin, beta 4 - 基因ID
- 3691
- 途径
- Integrin Complex
-