RUNX2 抗体 (AA 244-258)
Quick Overview for RUNX2 抗体 (AA 244-258) (ABIN2738787)
抗原
See all RUNX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 244-258
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特异性
- Human CBFA1 / RUNX2
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纯化方法
- Immunoaffinity purified
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免疫原
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A synthetic peptide corresponding to a sequence in the middle region of human RUNX2(244-258aa DRLSDLGRIPHPSMR). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Marmoset, Mouse, Ferret, Sheep, Hamster, Elephant, Rabbit, Horse, Pig, Guinea pig, Dog (100%), Turkey, Sparrow, Chicken, Platypus, Lizard (93%).
Type of Immunogen: Synthetic peptide -
亚型
- IgG
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应用备注
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Approved: WB (0.5 - 1 μg/mL)
Usage: Core binding factor A1(CBFA1/RUNX2) is a runt-like transcription factor essential for osteoblast differentiation. This protein is a member of the RUNX family of transcription factors and has a Runt DNA-binding domain. It is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. D'Souza et al.(1999) indicate a non-redundant role for Cbfa1 in tooth development that may be distinct from that in bone formation. In odontogenesis, Cbfa1 is not involved in the early signaling networks regulating tooth initiation and early morphogenesis but regulates key epithelial-mesenchymal interactions that control advancing morphogenesis and histodifferentiation of the epithelial enamel organ. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Sterile distilled water
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS, 2.5 % BSA, 0.025 % sodium azide/thimerosal.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
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- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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别名
- CBFA1 / RUNX2
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背景
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Name/Gene ID: RUNX2
Synonyms: RUNX2, AML3, CCD, CCD1, OSF2, PEBP2A1, PEBP2A2, PEA2-alpha A, PEBP2-alpha A, OSF-2, PEBP2A, PEBP2aA1, CBF-alpha-1, CBFA1, Oncogene AML-3, PEA2aA, PEBP2aA -
基因ID
- 860
抗原
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