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RUNX2 抗体 (AA 244-258)

This anti-RUNX2 antibody is a 兔 多克隆 antibody detecting RUNX2 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Pig, 兔, 猴, Hamster, Chimpanzee, Gibbon, Orang-Utan 和 绵羊.
产品编号 ABIN2738787
发货至: 中国

Quick Overview for RUNX2 抗体 (AA 244-258) (ABIN2738787)

抗原

See all RUNX2 抗体
RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

适用

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人, 小鼠, 大鼠, 犬, 豚鼠, 马, Pig, 兔, 猴, Hamster, Chimpanzee, Gibbon, Orang-Utan, 绵羊

宿主

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克隆类型

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多克隆

标记

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This RUNX2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 244-258

    特异性

    Human CBFA1 / RUNX2

    纯化方法

    Immunoaffinity purified

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human RUNX2(244-258aa DRLSDLGRIPHPSMR). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Marmoset, Mouse, Ferret, Sheep, Hamster, Elephant, Rabbit, Horse, Pig, Guinea pig, Dog (100%), Turkey, Sparrow, Chicken, Platypus, Lizard (93%).

    Type of Immunogen: Synthetic peptide

    亚型

    IgG
  • 应用备注

    Approved: WB (0.5 - 1 μg/mL)

    Usage: Core binding factor A1(CBFA1/RUNX2) is a runt-like transcription factor essential for osteoblast differentiation. This protein is a member of the RUNX family of transcription factors and has a Runt DNA-binding domain. It is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. D'Souza et al.(1999) indicate a non-redundant role for Cbfa1 in tooth development that may be distinct from that in bone formation. In odontogenesis, Cbfa1 is not involved in the early signaling networks regulating tooth initiation and early morphogenesis but regulates key epithelial-mesenchymal interactions that control advancing morphogenesis and histodifferentiation of the epithelial enamel organ.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Sterile distilled water

    浓度

    Lot specific

    缓冲液

    Lyophilized from PBS, 2.5 % BSA, 0.025 % sodium azide/thimerosal.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid freeze/thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
  • 抗原

    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

    别名

    CBFA1 / RUNX2

    背景

    Name/Gene ID: RUNX2

    Synonyms: RUNX2, AML3, CCD, CCD1, OSF2, PEBP2A1, PEBP2A2, PEA2-alpha A, PEBP2-alpha A, OSF-2, PEBP2A, PEBP2aA1, CBF-alpha-1, CBFA1, Oncogene AML-3, PEA2aA, PEBP2aA

    基因ID

    860
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