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Bcl-2 抗体 (AA 41-54)

BCL2 适用: 人, Pig, 猴, 犬, Chimpanzee WB, IHC, ELISA, FACS, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 8C8 unconjugated
产品编号 ABIN2738523
发货至: 中国
  • 抗原 See all Bcl-2 (BCL2) 抗体
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    抗原表位
    • 47
    • 34
    • 23
    • 22
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    • 18
    • 16
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 41-54
    适用
    • 423
    • 182
    • 175
    • 38
    • 33
    • 22
    • 21
    • 17
    • 16
    • 15
    • 8
    • 5
    • 5
    • 1
    • 1
    人, Pig, 猴, 犬, Chimpanzee
    宿主
    • 343
    • 103
    • 5
    • 2
    • 1
    小鼠
    克隆类型
    • 342
    • 111
    单克隆
    标记
    • 197
    • 33
    • 31
    • 25
    • 23
    • 14
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 9
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Bcl-2 antibody is un-conjugated
    应用范围
    • 368
    • 186
    • 161
    • 109
    • 107
    • 96
    • 92
    • 60
    • 59
    • 28
    • 24
    • 23
    • 18
    • 8
    • 8
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Human BCL2 / Bcl-2
    无交叉反应
    小鼠, 大鼠
    纯化方法
    Protein G purified
    免疫原
    A synthetic peptide, aa41-54 (GaaPAPGIFSSQPG-Cys) of human Bcl-2 protein. Percent identity by BLAST analysis: Human, Chimpanzee, Cat, Pig, Dog (100%), Gorilla, Orangutan, Bovine, Goat (91%), Galago (82%).

    Type of Immunogen: Synthetic peptide
    克隆位点
    8C8
    亚型
    IgG1 kappa
    Top Product
    Discover our top product BCL2 Primary Antibody
  • 应用备注
    Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)

    Usage: This antibody recognizes a protein of 25-26  kDa, identified as the Bcl-2 alpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative. ELISA: Order BSA-free format for coating.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2°C to 8°C.
  • 抗原
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    别名
    BCL2 / Bcl-2 (BCL2 产品)
    别名
    Bcl-2 antibody, PPP1R50 antibody, bcl-2 antibody, AW986256 antibody, C430015F12Rik antibody, D630044D05Rik antibody, D830018M01Rik antibody, BCL-2 antibody, Bcl2 antibody, BCL2, apoptosis regulator antibody, B cell leukemia/lymphoma 2 antibody, B-cell CLL/lymphoma 2a antibody, B-cell CLL/lymphoma 2 protein antibody, BCL2 antibody, Bcl2 antibody, bcl2a antibody, BCL-2 antibody
    背景
    Name/Gene ID: BCL2
    Family: Apoptosis

    Synonyms: BCL2, Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, B-cell lymphoma protein 2, Bcl-2, PPP1R50
    基因ID
    596
    途径
    MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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