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CCM2 抗体

CCM2 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 5H4 unconjugated
产品编号 ABIN2725247
发货至: 中国
  • 抗原 See all CCM2 抗体
    CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
    适用
    • 24
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 19
    • 4
    • 1
    小鼠
    克隆类型
    • 23
    • 1
    单克隆
    标记
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCM2 antibody is un-conjugated
    应用范围
    • 14
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    产品特性
    Homo sapiens cerebral cavernous malformation 2 (CCM2), transcript variant 2
    纯化方法
    Purified from mouse ascites fluids by affinity chromatography
    免疫原
    Full length human recombinant protein of human CCM2(NP_113631) produced in HEK293T cell.
    克隆位点
    5H4
    亚型
    IgG2b
    Top Product
    Discover our top product CCM2 Primary Antibody
  • 应用备注
    WB 1:2000, IF 1:100,
    说明

    The concentration of the product may vary between diferrent lots.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5-1.0 mg/mL
    缓冲液
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
    别名
    CCM2 (CCM2 产品)
    别名
    C7orf22 antibody, OSM antibody, malcavernin antibody, CCM2 antibody, BC029157 antibody, TUF2 antibody, vtn antibody, zgc:110233 antibody, CCM2 scaffolding protein antibody, cerebral cavernous malformation 2 antibody, malcavernin antibody, CCM2 antibody, Ccm2 antibody, LOC100304744 antibody, ccm2 antibody
    背景
    This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量
    48.7 kDa
    基因ID
    83605
    NCBI登录号
    NM_031443
    HGNC
    83605
    途径
    Cell-Cell Junction Organization
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