CYP2C8 抗体
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- 抗原 See all CYP2C8 抗体
- CYP2C8 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYP2C8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- This antibody detects endogenous levels of CYP2C8/9/18/19 protein. (region surrounding Met136)
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product CYP2C8 Primary Antibody
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anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) (AA 1-490) antibody
CYP2C8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) (AA 1-490) antibodyCYP2C8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) antibodyCYP2C8 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) (Internal Region) antibodyCYP2C8 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) (Internal Region) antibodyVerified CYP2C8 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) (AA 74-105), (N-Term) antibodyCYP2C8 适用: 人 WB 宿主: 兔 Polyclonal RB17003 unconjugated
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- 应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- CYP2C8 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))
- 别名
- CYP2C8 (CYP2C8 产品)
- 别名
- CPC8 antibody, CYPIIC8 antibody, MP-12/MP-20 antibody, CYP2C74 antibody, cpc8 antibody, cyp2c8 antibody, cypiic8 antibody, mp-12/mp-20 antibody, cytochrome P450 family 2 subfamily C member 8 antibody, Cytochrome P450 2C8 antibody, cytochrome P450, family 2, subfamily C, polypeptide 8 antibody, cytochrome P450 family 2 subfamily C member 8 S homeolog antibody, CYP2C8 antibody, CTN_0597 antibody, cyp2c8.1.S antibody, cyp2c8.1 antibody
- 背景
- The immunosuppressant cyclosporin A (CsA) forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of the CsA and is encoded by a single unique gene conserved from yeast to humans. CyPA is known for its involvement in T cell differentiation and proliferation and is highly expressed in brain. CyPA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.Cyclophilin B (CyPB) is a member of the cyclophilin family with specific N- and C-terminal extensions. Unlike CyPA, CyPB has a signal sequence leading to its translocation in the endoplasmic reticulum. CyPB is secreted in biological fluids such as blood or milk and binds to a specific receptor present on the human lymphoblastic cell line Jurkat and on human peripheral blood lymphocytes.Synonyms: CYPIIC8, Cytochrome P450 2C8, Cytochrome P450 IIC2, Cytochrome P450 MP-12/MP-20, Cytochrome P450 form 1, S-mephenytoin 4-hydroxylase
- 分子量
- approx. 60 kDa
- 基因ID
- 1558
- NCBI登录号
- NP_000761
- UniProt
- P10632
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