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EPH Receptor A7 抗体

The 兔 多克隆 anti-EPH Receptor A7 antibody is suitable to detect EPH Receptor A7 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN272234
发货至: 中国
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Quick Overview for EPH Receptor A7 抗体 (ABIN272234)

抗原

See all EPH Receptor A7 (EPHA7) 抗体
EPH Receptor A7 (EPHA7)

适用

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人, 小鼠, 大鼠

宿主

  • 65
  • 5
  • 1

克隆类型

  • 66
  • 5
多克隆

标记

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  • 1
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This EPH Receptor A7 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 特异性

    This antibody detects endogenous levels of EphA7 protein. (region surrounding Glu477)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    ELISA: 1/40000-1/60000. Western Blot: 1/500-1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    EPH Receptor A7 (EPHA7)

    别名

    EPHA7

    背景

    The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1 (Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8(Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3 (Cek10, Hek2), EphB4 (Htk), EphB5(Hek9) and EphB6 (Mep). EphAs are a family of receptor tyrosine kinases that are involved in axonal guidance during development. These receptors and their ligands, the ephrins, act via repulsive mechanisms to guide growing axons towards their appropriate targets and allow for the correct developmental connections to be made. Ligand binding to an Eph receptor results in tyrosine phosphorylation of the kinase domain, and repulsion of axonal growth cones and migrating cells. During neurulation, ephrin-A5 is coexpressed with its cognate receptor EphA7 in cells at the edges of the dorsal neural folds. Three different EphA7 splice variants, a full-length form and two truncated versions lacking kinase domains, are expressed in the neural folds.Synonyms: EHK3, EPH homology kinase 3, Ephrin type-A receptor 7, HEK11, Receptor protein-tyrosine kinase HEK11, Tyrosine-protein kinase receptor EHK-3

    分子量

    approx. 112 kDa

    基因ID

    2045

    NCBI登录号

    NP_004431

    UniProt

    Q15375

    途径

    RTK signaling
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