GIT2 抗体
-
- 抗原 See all GIT2 抗体
- GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This GIT2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects endogenous levels of GIT2 protein. (region surrounding Asp391)
- 交叉反应 （详细）
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product GIT2 Primary Antibody
-
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibody
GIT2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B5-B9 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibodyGIT2 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal M1 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibodyGIT2 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (Internal Region) antibodyGIT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-603) antibodyGIT2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (Internal Region) antibodyGIT2 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibodyGIT2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 401-498) antibodyGIT2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 714-749), (C-Term) antibodyGIT2 适用: 人 WB 宿主: 兔 Polyclonal RB48356 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 486-535) antibodyGIT2 适用: 人, 犬, Cow, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))
- 别名
- GIT2 (GIT2 产品)
- 别名
- CAT-2 antibody, CAT2 antibody, cat-2 antibody, xgit2 antibody, git2 antibody, si:dkey-234h16.4 antibody, 1500036H07Rik antibody, 5830420E16Rik antibody, 6430510B20Rik antibody, 9630056M03Rik antibody, B230104M05Rik antibody, mKIAA0148 antibody, zgc:158416 antibody, GIT ArfGAP 2 antibody, G protein-coupled receptor kinase interacting ArfGAP 2 antibody, G protein-coupled receptor kinase interacting ArfGAP 2a antibody, G protein-coupled receptor kinase-interactor 2 antibody, G protein-coupled receptor kinase interacting ArfGAP 2 L homeolog antibody, G protein-coupled receptor kinase interacting ArfGAP 2b antibody, GIT2 antibody, git2 antibody, git2a antibody, Git2 antibody, git2.L antibody, git2b antibody
- 背景
- Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. G protein-coupled receptor kinases(GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade. GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking. GIT1 overexpression results in reduced internalization and resensitization of β2-adrenergic receptor, thus reducing β2-adrenergic receptor signaling.Synonyms: ARF GTPase-activating protein GIT2, CAT2, Cool-interacting tyrosine-phosphorylated protein 2, G protein-coupled receptor kinase-interactor 2, GRK-interacting protein 2, KIAA0148
- 分子量
- approx. 84 kDa
- 基因ID
- 9815
- NCBI登录号
- NP_001128685
- UniProt
- Q14161
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
-
