CDKL1 抗体
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- 抗原 See all CDKL1 抗体
- CDKL1 (Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1))
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDKL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of KKIALRE protein. (region surrounding asn301)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Rat.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product CDKL1 Primary Antibody
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anti-Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1) (AA 259-358) antibody
CDKL1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 5B11 unconjugated
anti-Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1) (AA 285-316), (C-Term) antibodyCDKL1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3517 unconjugated
anti-Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1) (AA 259-358) antibodyCDKL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1) (C-Term) antibodyCDKL1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1) (C-Term) antibodyCDKL1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1) (AA 259-358) antibodyCDKL1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1) (C-Term) antibodyCDKL1 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1) (AA 259-358) antibodyCDKL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8B2 unconjugated
anti-Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1) (AA 281-330) antibodyCDKL1 适用: 人, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- CDKL1 (Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1))
- 别名
- CDKL1 (CDKL1 产品)
- 别名
- CDKL1 antibody, KKIALRE antibody, P42 antibody, 4933411O17Rik antibody, cyclin dependent kinase like 1 antibody, cyclin-dependent kinase-like 1 (CDC2-related kinase) antibody, CDKL1 antibody, cdkl1 antibody, Cdkl1 antibody
- 背景
- The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.Synonyms: Cyclin-dependent kinase-like 1, KKIALRE, Protein kinase p42 KKIALRE, Serine/threonine-protein kinase KKIALRE
- 分子量
- approx. 42 kDa
- 基因ID
- 8814
- NCBI登录号
- NP_004187
- UniProt
- Q00532
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