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CSNK1A1 抗体

The 兔 多克隆 anti-CSNK1A1 antibody is suitable to detect CSNK1A1 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IF 和 IHC (p).
产品编号 ABIN272195
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CSNK1A1 抗体 (ABIN272195)

抗原

See all CSNK1A1 抗体
CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

适用

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人, 大鼠, 小鼠

宿主

  • 114
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  • 1
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克隆类型

  • 110
  • 13
多克隆

标记

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This CSNK1A1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of Casein Kinase Iα protein. (region surrounding Phe158)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

    别名

    Casein Kinase I alpha

    背景

    Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIα, β, γ, e and δ, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The a catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.Synonyms: CK1, CKI-alpha, CSNK1A1

    分子量

    approx. 34, 42 kDa

    基因ID

    1452

    NCBI登录号

    NP_001020276

    UniProt

    P48729

    途径

    WNT signaling, Hedgehog Signaling
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