AFT7 抗体
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- 抗原 See all AFT7 抗体
- AFT7 (Activating Transcription Factor 7 (AFT7))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AFT7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of ATF-7 protein. (region surrounding Phe74)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product AFT7 Primary Antibody
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anti-Activating Transcription Factor 7 (AFT7) (AA 50-270) antibody
AFT7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (N-Term) antibodyAFT7 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (AA 1-117) antibodyAFT7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (AA 68-96), (N-Term) antibodyAFT7 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB21430 unconjugated
anti-Activating Transcription Factor 7 (AFT7) (AA 68-96) antibodyAFT7 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (C-Term) antibodyVerified AFT7 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) antibodyAFT7 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (AA 1-483) antibodyAFT7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (C-Term) antibodyAFT7 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 7 (AFT7) (AA 397-446) antibodyAFT7 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 兔, 豚鼠, Bat, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- AFT7 (Activating Transcription Factor 7 (AFT7))
- 别名
- ATF7 (AFT7 产品)
- 别名
- ATFA antibody, 1110012F10Rik antibody, 9430065F09Rik antibody, AI549878 antibody, C130020M04Rik antibody, ATF7 antibody, fa97a09 antibody, fc25b12 antibody, wu:fa97a09 antibody, wu:fc25b12 antibody, atfa antibody, activating transcription factor 7 antibody, activating transcription factor 7b antibody, ATF7 antibody, Atf7 antibody, atf7b antibody, atf7 antibody
- 背景
- Eukaryotic gene transcription is regulated by sequence-specific transcription factors, which bind modular cis acting promoter and enhancer elements. The cAMP response element (CRE) consists of the palindromic octanucleotide TGACGTCA. There are several CRE binding proteins within the ATF/CREB family, including CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2 and ATF-3. A novel basic leucine zipper (bZIP) protein, designated ATF-7, is closely related to members of the ATF/CREB family of bZIP proteins, with highest homology to ATF-4. ATF-7 physically interacts with the PRL-1 protein-tyrosine phosphatase (PTPase), which is a predominately nuclear, farnesylated PTPase. ATF-7 homodimers bind specifically to CRE elements. ATF-7 is expressed in a number of different tissues and is expressed in association with differentiation. ATF-7 and PRL-1 interact with each other through the bZIP region of ATF-7 and the phosphatase domain of PRL-1. In addition, PRL-1 is able to dephosphorylate ATF-7 in vitro.Synonyms: ATF-7, ATF-A, ATFA, Activating transcription factor 7, Cyclic AMP-dependent transcription factor ATF-7, cAMP-dependent transcription factor ATF-7
- 分子量
- approx. 35, 53 kDa
- 基因ID
- 11016
- NCBI登录号
- NP_001123531
- UniProt
- P17544
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