Musculin 抗体
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- 抗原 See all Musculin (MSC) 抗体
- Musculin (MSC)
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Musculin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Musculin protein. (region surrounding Arg167)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product MSC Primary Antibody
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anti-Musculin (MSC) (Internal Region) antibody
MSC 适用: 人, 大鼠 ELISA, WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Musculin (MSC) (AA 3-143) antibodyMSC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Musculin (MSC) (AA 1-100) antibodyMSC 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4D7 unconjugated
anti-Musculin (MSC) (C-Term) antibodyMSC 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Musculin (MSC) (C-Term) antibodyMSC 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Musculin (MSC) (AA 103-188) antibodyMSC 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1D1 unconjugated
anti-Musculin (MSC) (C-Term) antibodyVerified MSC 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Musculin (MSC) (AA 166-194), (C-Term) antibodyMSC 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB37175 unconjugated
anti-Musculin (MSC) (AA 131-180) antibodyMSC 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- Musculin (MSC)
- 别名
- Musculin (MSC 产品)
- 别名
- Msc antibody, MSC antibody, abf1 antibody, myor antibody, abf-1 antibody, ABF-1 antibody, ABF1 antibody, MYOR antibody, bHLHa22 antibody, MyoR antibody, musculin antibody, putative musculin antibody, msc antibody, musculin antibody, Smp_022610 antibody, MSC antibody, Msc antibody
- 背景
- Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins, known to play an important role in the regulation of muscle cell development, includes MyoD, myogenin and musculin (also designated MyoR). Members of this group of transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many musclespecific terminal differentiation genes. MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to represses MyoD activity, which then results in the delayed expression of muscle-specific genes. Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is down regulated during myogenesis and at the onset of terminal differentiation.Synonyms: ABF-1, ABF1, Activated B-cell factor 1, MSC
- 分子量
- approx. 22 kDa
- 基因ID
- 9242
- NCBI登录号
- NP_005089
- UniProt
- O60682
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