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KLF11 抗体

KLF11 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272134
发货至: 中国
  • 抗原 See all KLF11 抗体
    KLF11 (Kruppel-Like Factor 11 (KLF11))
    适用
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    人, 小鼠
    宿主
    • 43
    • 4
    克隆类型
    • 43
    • 4
    多克隆
    标记
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    This KLF11 antibody is un-conjugated
    应用范围
    • 36
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of TIEG2 protein. (region surrounding Phe6)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product KLF11 Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    KLF11 (Kruppel-Like Factor 11 (KLF11))
    别名
    KLF11 / TIEG2 (KLF11 产品)
    别名
    FKLF antibody, FKLF1 antibody, MODY7 antibody, TIEG2 antibody, Tieg3 antibody, 9830142A17 antibody, D12Ertd427e antibody, Tieg2 antibody, Tieg2b antibody, Tcfcp2l2 antibody, KLF11 antibody, klf11 antibody, si:dkey-81b15.5 antibody, tieg3 antibody, wu:fc45c07 antibody, wu:fj44b12 antibody, zgc:153255 antibody, fklf antibody, fklf1 antibody, mody7 antibody, tieg2 antibody, MGC145216 antibody, TIEG-2 antibody, zgc:154048 antibody, Kruppel like factor 11 antibody, Kruppel-like factor 11 antibody, Kruppel-like factor 11 L homeolog antibody, Kruppel-like factor 11a antibody, Krueppel-like factor 11 antibody, Kruppel-like factor 11b antibody, KLF11 antibody, Klf11 antibody, klf11.L antibody, klf11a antibody, klf11 antibody, LOC100194692 antibody, klf11b antibody
    背景
    Originally isolated from osteoblastic cells, the TGF-beta-inducible early gene-1 (TIEG1) is a Krupel-like zinc finger transcription factor-encoding gene which regulates cellular growth and differentiation. TIEG1 is regulated as an early response gene by TGFβ1. It is expressed in both acinar and ductular epithelial cells from exocrine pancreas and may serve as an early response gene in pancreatic cell lines. Further, overexpression of TIEG1 in TGFβ-sensitive epithelial cells induces apoptosis. TIEG1 and EGR-α are expressedfrom alternate promoters of the same gene. TIEG1 and EGR-α are both highly expressed in human fetal osteoblast cells. TIEG1 is additionally expressed at high levels in PBLs, spleen and colon, and at lower levels in thymus, small intestine, ovary, prostate and skeletal muscle. The nuclear TIEG2 protein, which shares significant homology with TIEG1, was originally isolated from globin-expressing human fetal eryth-roid cells. TIEG2 is also expressed in fetal liver. Overexpression of TIEG2 in cultured epithelial cells inhibits cellular proliferation, TIEG2 expression is upregulated by TGFβ1 and serum deprivation.Synonyms: FKLF, Krueppel-like factor 11, TGFB-inducible early growth response protein 2, TIEG-2, Transforming growth factor-beta-inducible early growth response protein 2
    分子量
    approx. 55 kDa
    基因ID
    8462
    NCBI登录号
    NP_001171187
    UniProt
    O14901
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