BACH1 抗体
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- 抗原 See all BACH1 抗体
- BACH1 (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BACH1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of BACH1 protein. (region surrounding Leu160)
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product BACH1 Primary Antibody
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anti-BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) antibody
BACH1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) (AA 396-492) antibodyBACH1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) (Internal Region) antibodyBACH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) antibodyBACH1 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) (AA 1-320) antibodyBACH1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) (AA 1-320) antibodyBACH1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) (Center) antibodyBACH1 适用: 人, 猴 WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
anti-BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) (AA 1-320) antibodyBACH1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) (C-Term) antibodyBACH1 适用: 人, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) (AA 131-180) antibodyBACH1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 20000approx. 140000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- BACH1 (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1))
- 别名
- BACH1 (BACH1 产品)
- 别名
- zgc:112205 antibody, BACH1 antibody, 6230421P05Rik antibody, AI323795 antibody, BACH-1 antibody, BTB domain and CNC homolog 1 antibody, BTB and CNC homology 1, basic leucine zipper transcription factor 1 b antibody, BTB and CNC homology 1, basic leucine zipper transcription factor 1 antibody, BACH1 antibody, bach1b antibody, bach1 antibody, Bach1 antibody
- 背景
- Members of the small Maf family (MafK, MafF, and MafG) are basic region leucine zipper (bZip) proteins that can function as transcriptional activators or repressors. They dimerize with other proteins and bind DNA to either represse or activate transcription depending on the dimer compositions. BACH1 and BACH2, heterodimerization partners of MafK, are members of a novel family of BTB/POZ-basic region leucine zipper (bzip) factors. BACH1 and BACH2 have significant similarity to each other in BTB domain and Cap'n' collar-type bZip domain but are otherwise divergent. BACH1 appears ubiquitous, whereas BACH2 is restricted to monocytes, neuronal cells and is abundantly expressed in the early stages of B-cell differentiation. BACH2, a 841 amino acid polypeptide, is an Nrf2-related transcription repressor and a tissue-specific partner of the Maf oncoprotein family. In culture cells, BACH2 is localized to the cytoplasm through its C-terminal cytoplasmic localization signal (CLS). Oxidative stressors aborted the CLS activity and induce nuclear accumulation of BACH2, which mediates nucleocytoplasmic communciation to couple oxidative stress and transcription repression in mammalian cells. BACH2 heterodimerizes with MAZR through its BTB/POZ domain to activate transcription. BACH2 also plays an important role in the regulation of B cell development.Synonyms: BTB and CNC homolog 1, HA2303, Transcription regulator protein BACH1, basic leucine zipper transcription factor 1
- 分子量
- approx. 83 kDa
- 基因ID
- 571
- NCBI登录号
- NP_001177
- UniProt
- O14867
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