PFKFB2 抗体
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- 抗原 See all PFKFB2 抗体
- PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PFKFB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of PFKFB2 protein. (region surrounding Pro479)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product PFKFB2 Primary Antibody
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anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 360-505) antibody
PFKFB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 446-505) antibodyPFKFB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (pSer483) antibodyPFKFB2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 467-497), (C-Term) antibodyPFKFB2 适用: 人 WB 宿主: 兔 Polyclonal RB4033 unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (pSer483) antibodyPFKFB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (C-Term) antibodyPFKFB2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (C-Term) antibodyPFKFB2 适用: 人, 小鼠, 大鼠, 猴, 犬, 马, 豚鼠, 兔, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 336-385) antibodyPFKFB2 适用: 人, 小鼠, 大鼠, 猴, 犬, 马, 斑马鱼, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 1-30), (N-Term) antibodyPFKFB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4031-4032 unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (N-Term) antibodyPFKFB2 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))
- 别名
- PFKFB2 (PFKFB2 产品)
- 别名
- pfkfb2 antibody, zgc:56282 antibody, PFK-2/FBPase-2 antibody, 4930568D07Rik antibody, RH2K antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 antibody, pfkfb2a antibody, PFKFB2 antibody, pfkfb2 antibody, Pfkfb2 antibody
- 背景
- Phosphofructokinases (PFK) are regulatory glycolytic enzymes that convert fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. Human PFK-1 is tetrameric and isoenzymes include, PFK-1 muscle (PFKM, PFK-A), PFK-1 liver (PFKL, PFK-B) and PFK-1 platelet (PFKP, PFK-C, PFKF). PFK-1 is inhibited by ATP and citrate (from the tricarboxylic acid cycle). PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose 2,6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regulator for PFK-1. PFK-2 catalyzes the synthesis of fructose 2,6-bisphosphate and contains fructose 2,6-biphosphatase activity that catalyzes the degradation of fructose 2,6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, inducible PFK-2) and PFK-2 testis (PFKFB4).Synonyms: 6-biphosphatase 2, 6-phosphofructo-2-kinase/fructose-2, PFK-2/FBPase-2, PFK/FBPase 2, PFKFB cardiac
- 分子量
- approx. 58 kDa
- 基因ID
- 5208
- NCBI登录号
- NP_001018063
- UniProt
- O60825
- 途径
- PI3K-Akt Signaling, Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process
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