IRAK1 抗体
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- 抗原 See all IRAK1 抗体
- IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IRAK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 特异性
- This antibody detects endogenous levels of IRAK1 protein. (region surrounding Thr381)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product IRAK1 Primary Antibody
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anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 301-400) antibody
IRAK1 适用: 人, 大鼠 ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 530-693) antibodyIRAK1 适用: 人 WB, ELISA, IHC (p), IP, IF 宿主: 小鼠 Monoclonal 3F7 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 530-693) antibodyIRAK1 适用: 人 WB, ELISA, IHC (p), IP, IF, RNAi 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 530-693) antibodyIRAK1 适用: 人 WB, IHC (p), IP, IF, EIA 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (pThr209) antibodyIRAK1 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 348-381), (pSer376) antibodyIRAK1 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB56575 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 424-633) antibodyIRAK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 683-712), (C-Term) antibodyIRAK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB02337 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (AA 683-712) antibodyIRAK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (pThr387) antibodyIRAK1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
- 别名
- IRAK1 (IRAK1 产品)
- 别名
- IRAK1 antibody, IRAK antibody, pelle antibody, AA408924 antibody, IRAK-1 antibody, IRAK1-S antibody, Il1rak antibody, Plpk antibody, mPLK antibody, RGD1563841 antibody, interleukin 1 receptor associated kinase 1 antibody, interleukin-1 receptor-associated kinase 1 antibody, IRAK1 antibody, irak1 antibody, Irak1 antibody
- 背景
- Three structurally related ligands for IL-1Rs have been described. These include two agonists, IL-1alpha and IL-1beta, and a specific receptor antagonist, IL-1Ralpha. Two distinct receptors designated IL-1RI and IL-1RII have been identified, each of which belong to the Ig superfamily. The preponderance of evidence suggests IL-1RI to be the functional IL-1 receptor. Binding of IL-1 to its cognate receptor results in the activation of the NFkappaB signaling pathway. The IL-1-dependent kinase termed IRAK (for IL-1 receptor-associated kinase) co-immunoprecipitates with activated IL-1RI and has been implicated as an upstream mediator of NFkappaB activation. Additional support for this assertion comes from the fact that a related Drosophila protein, Pelle, is a known upstream activator of Dorsal, the Drosophila homolog of NFkappaB.Synonyms: IRAK, IRAK-1, Interleukin-1 receptor-associated kinase 1
- 分子量
- approx. 76 kDa
- 基因ID
- 3654
- NCBI登录号
- NP_001020413
- UniProt
- P51617
- 途径
- NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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