SAE1 抗体
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- 抗原 See all SAE1 抗体
- SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SAE1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of AOS1 protein. (region surrounding Leu247)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product SAE1 Primary Antibody
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anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) (AA 1-346) antibody
SAE1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G4-1G5 unconjugated
anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) antibodyKO Validated SAE1 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) (Internal Region) antibodySAE1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) (AA 1-346) antibodySAE1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) (AA 300-329), (C-Term) antibodySAE1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2887-RB2888 unconjugated
anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) (AA 1-346) antibodySAE1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) antibodySAE1 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 9D8 unconjugated Recombinant Antibody
anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) antibodySAE1 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G8 unconjugated
anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) antibodySAE1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) (Center) antibodySAE1 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IF: 1: 50-1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- SAE1 (SUMO1 Activating Enzyme Subunit 1 (SAE1))
- 别名
- SAE1 / AOS1 (SAE1 产品)
- 别名
- AOS1 antibody, HSPC140 antibody, SUA1 antibody, UBLE1A antibody, 2400010M20Rik antibody, 2610044L12Rik antibody, AL033372 antibody, AW743391 antibody, D7Ertd177e antibody, Sua1 antibody, Uble1a antibody, Aos1p antibody, Sua1p antibody, aos antibody, sae2a antibody, uble1a antibody, wu:fa28b04 antibody, zgc:86633 antibody, SUMO1 activating enzyme subunit 1 antibody, SUMO1 activating enzyme subunit 1 L homeolog antibody, SAE1 antibody, Sae1 antibody, sae1.L antibody, sae1 antibody
- 背景
- Proteolytic degradation by the ubiquitin (Ub) system is essential for normal cell cycle progression, cellular differentiation and stress responses. Proteins conjugated to Ub are marked for progressive degradation by the 26S Proteosome. Ubiquitin-like 1-activating enzyme E1A, also designated SUMO-1-activating enzyme or AOS-1, belongs to the ubiquitin-activating E1 family of proteins and plays an important role in the first step of the UBL1 conjugation pathway. AOS-1, which is a dimeric enzyme, functions as a UBLI E1 ligase, mediating the ATP-dependent activation of UBL1. It can bind with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1.Synonyms: SUA1, SUMO-activating enzyme subunit 1, UBLE1A, Ubiquitin-like 1-activating enzyme E1A
- 分子量
- approx. 38 kDa
- 基因ID
- 10055
- NCBI登录号
- NP_005491
- UniProt
- Q9UBE0
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