THRA 抗体
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- 抗原 See all THRA 抗体
- THRA (Thyroid Hormone Receptor, alpha (THRA))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This THRA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Thyroid Hormone Receptor protein. (region surrounding Ala19)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product THRA Primary Antibody
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anti-Thyroid Hormone Receptor, alpha (THRA) (AA 87-178) antibody
THRA 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Thyroid Hormone Receptor, alpha (THRA) antibodyTHRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 unconjugated
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (HRP)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 HRP
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (FITC)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 FITC
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (Alkaline Phosphatase (AP))THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 Alkaline Phosphatase (AP)
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (Biotin)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 Biotin
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (PE)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 PE
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (PerCP)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 PerCP
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (APC)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 APC
anti-Thyroid Hormone Receptor, alpha (THRA) antibody (Atto 594)THRA 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal H43 Atto 594
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- 应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- THRA (Thyroid Hormone Receptor, alpha (THRA))
- 别名
- THRA / ERBA1 (THRA 产品)
- 别名
- AR7 antibody, CHNG6 antibody, EAR7 antibody, ERB-T-1 antibody, ERBA antibody, ERBA1 antibody, NR1A1 antibody, THRA1 antibody, THRA2 antibody, c-ERBA-1 antibody, C-ERBA-ALPHA antibody, TRalpha antibody, c-erba antibody, erba antibody, nr1a1-A antibody, thra-A antibody, thra1 antibody, TR[a]1 antibody, nr1a1 antibody, thra antibody, thral antibody, tra antibody, tra1 antibody, wu:fb59g07 antibody, Thra1 antibody, 6430529J03Rik antibody, AW259572 antibody, Erba antibody, Nr1a1 antibody, Rvr antibody, T3R[a] antibody, T3Ralpha antibody, Thra2 antibody, C-ERBA ALPHA1 antibody, Thra antibody, fTHRalphaA antibody, nr1a1-a antibody, thyroid hormone receptor, alpha antibody, thyroid hormone receptor, alpha L homeolog antibody, thyroid hormone receptor alpha a antibody, thyroid hormone receptor alpha antibody, thyroid hormone receptor alpha-A antibody, THRA antibody, thra.L antibody, thraa antibody, Thra antibody, tr-alpha antibody, LOC109641414 antibody
- 背景
- Thyroid hormone nuclear receptors (TRs) are ligand-dependent transcription factors which regulate growth, differentiation and development and represent members of the steroid/retinoic acid superfamily. The two genes encoding TRs identified to date, TRα and TRβ, have been mapped to human chromosomes 17 and 3, respectively. TRs bind to thyroid hormone response elements (TREs) with half-site binding motifs in the orientation of palindromes, direct repeats or inverted palindromes. The affinities of binding are both variable and influenced differentially by 3,5,3'-triiodo-L-thyronine (T3). Transcriptional regulation by TRs is also modulated by heterodimerization with TR nuclear accessory proteins, the most extensively characterized of which are the retinoid X receptors (RXRα, RXRβ and RXRγ). To a certain extent, this activity is regulated by differential phosphorylation of TRs. Thus, not only are the biological activities of TRs regulated by heterodimerization with RXRs, but in addition, the gene regulatory activities of TRs are linked to other hormonal pathways. TRα1 can display both a nuclear and undefined cytoplasmic location, and is the only TR that is imported into the mitochondrial matrix.Synonyms: C-erbA-alpha, EAR-7, EAR7, NR1A1, Nuclear receptor subfamily 1 group A member 1, THRA1, THRA2, Thyroid hormone receptor alpha, c-erbA-1
- 分子量
- approx. 55 kDa
- 基因ID
- 7067
- NCBI登录号
- NP_001177847
- UniProt
- P10827
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development
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