电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PAX5 抗体

PAX5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN271778
发货至: 中国
  • 抗原 See all PAX5 抗体
    PAX5 (Paired Box 5 (PAX5))
    适用
    • 95
    • 47
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 79
    • 14
    • 1
    • 1
    克隆类型
    • 69
    • 26
    多克隆
    标记
    • 55
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAX5 antibody is un-conjugated
    应用范围
    • 63
    • 47
    • 28
    • 15
    • 14
    • 14
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of Pax-5 protein. (region surrounding Asp2)
    交叉反应 (详细)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product PAX5 Primary Antibody
  • 应用备注
    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    PAX5 (Paired Box 5 (PAX5))
    别名
    PAX5 (PAX5 产品)
    别名
    PAX5 antibody, BSAP antibody, Pax-5 antibody, pax5-a antibody, RGD1565236 antibody, EBB-1 antibody, KLP antibody, Pax[Zf-b] antibody, noi antibody, pax2.1 antibody, pax2a antibody, paxzf-b antibody, paired box 5 antibody, paired box 5 L homeolog antibody, PAX5 antibody, pax5.L antibody, Pax5 antibody, pax5 antibody
    背景
    The Pax gene family of nuclear transcription factors is comprised of nine family members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. For example, the human Pax-5 gene encodes a B cell lineage specific protein called B cell specific activator protein or BSAP, which is expressed in pro-B, pre-B and mature B lymphocytes but not in plasma cells. BSAP functions to regulate not only B cell development, but also influences the balance between immunoglobulin secretion and B cell proliferation. Overexpression of BSAP has been implicated in cellular transformation, and in the case of small lyphocytic lymphomas with plasmacytoid differentiation, a t(9,14)(p13,q32) translocation resulting in the deregulation of Pax-5 gene expression has been detected. The gene which encodes Pax-5 maps to human chromosome 9p13.Synonyms: B-cell-specific transcription factor, BSAP, Paired box protein Pax-5, Pax-5
    分子量
    approx. 40 kDa
    基因ID
    5079
    NCBI登录号
    NP_057953
    UniProt
    Q02548
You are here:
客服