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TNF alpha 抗体

TNF alpha 适用: 小鼠, 大鼠, 兔 WB, ELISA, IP, Neut, Inhibition 宿主: Armenian Hamster Monoclonal TN3 unconjugated
产品编号 ABIN2689936
发货至: 中国
  • 抗原 See all TNF alpha 抗体
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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    小鼠, 大鼠, 兔
    宿主
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    Armenian Hamster
    克隆类型
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    单克隆
    标记
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    This TNF alpha antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Neutralization (Neut), Blocking Antibody (Inhibition)
    品牌
    BD Pharmingen™
    产品特性
    The TN3-19.12 antibody reacts with rat and mouse tumor-necrosis factor (TNF) proteins (also known as TNF-α) . Moreover, the TN3-19.12 antibody is reported to crossreact with rabbit TNF, but it does not crossreact with mouse lymphotoxin-α (LT-α, also known as TNF-β) nor with human TNF. The immunogen used to generate the TN3-19.12 hybridoma was E. coli-expressed, purified recombinant mouse TNF protein. This monoclonal antibody has been reported to neutralize the bioactivities of mouse, rat and rabbit TNF. This antibody is routinely tested by ELISA. Other applications were tested during antibody development only or reported in the literature.

    BD Pharmingen™ Purified Hamster Anti-Mouse/Rat TNF - Purified - Clone TN3-19.12 - Isotype Armenian Hamster IgG1, λ1 - Reactivity Ms, Rat, Rab - 0.5 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Recombinant mouse TNF protein
    克隆位点
    TN3
    亚型
    IgG1 lambda
    Top Product
    Discover our top product TNF alpha Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Takahashi, Kapás, Fang, Krueger: "An anti-tumor necrosis factor antibody suppresses sleep in rats and rabbits." in: Brain research, Vol. 690, Issue 2, pp. 241-4, (1996) (PubMed).

    Ferran, Dautry, Mérite, Sheehan, Schreiber, Grau, Bach, Chatenoud: "Anti-tumor necrosis factor modulates anti-CD3-triggered T cell cytokine gene expression in vivo." in: The Journal of clinical investigation, Vol. 93, Issue 5, pp. 2189-96, (1994) (PubMed).

    Rabinovici, Bugelski, Esser, Hillegass, Griswold, Vernick, Feuerstein: "Tumor necrosis factor-alpha mediates endotoxin-induced lung injury in platelet activating factor-primed rats." in: The Journal of pharmacology and experimental therapeutics, Vol. 267, Issue 3, pp. 1550-7, (1994) (PubMed).

    Leiby, Fortier, Crawford, Schreiber, Nacy: "In vivo modulation of the murine immune response to Francisella tularensis LVS by administration of anticytokine antibodies." in: Infection and immunity, Vol. 60, Issue 1, pp. 84-9, (1992) (PubMed).

    Merrick, He, Craig, Clark, Corsini, Rosenthal, Mansfield, Selkirk: "Two dimensional gel electrophoresis of cellular and secreted proteins from rat alveolar macrophages after lipopolysaccharide treatment." in: Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society, Vol. 2, Issue 6, pp. 177-87, (1992) (PubMed).

    Sheehan, Ruddle, Schreiber: "Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 142, Issue 11, pp. 3884-93, (1989) (PubMed).

  • 抗原
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    别名
    TNF (TNF alpha 产品)
    别名
    DIF antibody, TNF-alpha antibody, TNFA antibody, TNFSF2 antibody, RATTNF antibody, Tnfa antibody, tnf antibody, TNF-a antibody, TNFalpha antibody, Tnfsf1a antibody, TNFa antibody, cTNF antibody, Tnf-alpha antibody, tnfa-like antibody, TNF-ALPHA antibody, dif antibody, tnfa antibody, xtnf antibody, tnfsf2 antibody, tnf-alpha antibody, Cachectin antibody, tumor necrosis factor antibody, tumor necrosis factor b (TNF superfamily, member 2) antibody, tumor necrosis factor alpha antibody, tumor necrosis factor a (TNF superfamily, member 2) antibody, TNF antibody, Tnf antibody, tnf antibody, tnfb antibody, tnf-alpha antibody, LOC103694380 antibody, tnfa antibody
    途径
    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
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