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TCR gamma/delta 抗体

TCR gamma/delta 适用: 人 FACS, IHC (fro) 宿主: 小鼠 Monoclonal B1 unconjugated
产品编号 ABIN2689920
发货至: 中国
  • 抗原 See all TCR gamma/delta products
    TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))
    适用
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    宿主
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    小鼠
    克隆类型
    • 60
    单克隆
    标记
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    This TCR gamma/delta antibody is un-conjugated
    应用范围
    • 60
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    品牌
    BD Pharmingen™
    产品特性
    Recognizes the γ/δ T-cell receptor (TCR). This receptor complex consists of two disulfide-linked glycoproteins, a γ chain (45-60 kDa) and a δ subunit (40-60 kDa). γ/δ TCR is expressed in less than 10 % of human peripheral T cells. The physiological significance of γ/δ+ T cells is still unknown. There is evidence indicating that these cells recognize bacterial ligands and some tumor cells. Reports suggest that γ/δ+ T cells may play a role in the immune reaction during infection and in regulation of pathphysiological autoimmune responses. Due to the fact that CD3 and TCRγδ antibodies may recognize epitopes which are very close to each other and that CD3 was interfering with the clone B1 antibody binding but not with the clone 11F2 antibody, we recommend to use clone 11F2 antibody to perform double staining TCRγδ and CD3. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed on a FACScan

    BD Pharmingen™ Purified Mouse Anti-Human TCR γδ - Purified - Clone B1 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    B1
    亚型
    IgG1 kappa
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Kabelitz: "Function and specificity of human gamma/delta-positive T cells." in: Critical reviews in immunology, Vol. 11, Issue 5, pp. 281-303, (1992) (PubMed).

    Kabelitz, Pechhold, Bender, Wesselborg, Wesch, Friese, Janssen: "Activation and activation-driven death of human gamma/delta T cells." in: Immunological reviews, Vol. 120, pp. 71-88, (1991) (PubMed).

  • 抗原
    TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))
    别名
    TCR Gammadelta (TCR gamma/delta 产品)
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