(9 references)-
- 抗原 See all H2-D1 抗体
- H2-D1 (Histocompatibility 2, D Region Locus 1 (H2-D1))
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This H2-D1 antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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The 28-14-8 antibody reacts with the α3 domain of the H-2D[b] MHC class I alloantigen. The antibody binds to H-2D[b] in the presence or absence of the β2 microglobulin chain. It cross-reacts with the α3 domain of H-2L[d], but not with K[d] or D[d], and with H-2D[q] and/or L[q]. Reactivity with haplotypes k, f, p, r, and s has not been observed. mAb 28-14-8 has been shown to block H-2L[d]- specific and H- 2L[d]-restricted antigen-specific lysis of target cells by cytotoxic T lymphocytes (CTL), but it does not block recognition of H-2L[d] positive target cells by Ly-6G2-positive NK cells.
BD Pharmingen™ Biotin Mouse Anti-Mouse H-2D[b] - Biotin - Clone 28-14-8 - Isotype Mouse IgG2a, κ - Reactivity Ms - 0.5 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- C3H.SW mouse splenocytes
- 克隆位点
- 28-14
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product H2-D1 Primary Antibody
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anti-Histocompatibility 2, D Region Locus 1 (H2-D1) (AA 25-311) antibody
H2-D1 适用: 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Histocompatibility 2, D Region Locus 1 (H2-D1) antibody (PE)H2-D1 适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 28-14-8 PE
anti-Histocompatibility 2, D Region Locus 1 (H2-D1) antibody (APC)H2-D1 适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 28-14-8 APC
anti-Histocompatibility 2, D Region Locus 1 (H2-D1) antibodyH2-D1 适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 28-14-8 unconjugated
anti-Histocompatibility 2, D Region Locus 1 (H2-D1) antibody (Biotin)H2-D1 适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 28-14-8 Biotin
anti-Histocompatibility 2, D Region Locus 1 (H2-D1) antibody (FITC)H2-D1 适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 28-14-8 FITC
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "Fibroblasts as efficient antigen-presenting cells in lymphoid organs." in: Science (New York, N.Y.), Vol. 268, Issue 5215, pp. 1343-7, (1995) (PubMed).
: "Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2)" in: The Journal of experimental medicine, Vol. 182, Issue 2, pp. 293-303, (1995) (PubMed).
: "Beta 2-microglobulin is not required for cell surface expression of the murine class I histocompatibility antigen H-2Db or of a truncated H-2Db." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 19, pp. 7447-51, (1986) (PubMed).
: "Domain interactions of H-2 class I antigens alter cytotoxic T-cell recognition sites." in: Nature, Vol. 309, Issue 5965, pp. 279-81, (1984) (PubMed).
: "Exon shuffling: mapping polymorphic determinants on hybrid mouse transplantation antigens." in: Nature, Vol. 300, Issue 5894, pp. 755-7, (1983) (PubMed).
: "Product of a transferred H-2Ld gene acts as restriction element for LCMV-specific killer T cells." in: Nature, Vol. 297, Issue 5865, pp. 415-7, (1982) (PubMed).
: "Specific recognition of the product of a transferred major histocompatibility complex gene by cytotoxic T lymphocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 79, Issue 11, pp. 3613-7, (1982) (PubMed).
: "Monoclonal antibodies to mouse MHC antigens. II. Antibodies to the H-2Ld antigen, the products of a third polymorphic locus of the mouse major histocompatibility complex." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 125, Issue 6, pp. 2473-7, (1981) (PubMed).
: "Monoclonal antibodies to mouse MHC antigens. III. Hybridoma antibodies reacting to antigens of the H-2b haplotype reveal genetic control of isotype expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 126, Issue 1, pp. 317-21, (1981) (PubMed).
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: "Fibroblasts as efficient antigen-presenting cells in lymphoid organs." in: Science (New York, N.Y.), Vol. 268, Issue 5215, pp. 1343-7, (1995) (PubMed).
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- 抗原
- H2-D1 (Histocompatibility 2, D Region Locus 1 (H2-D1))
- 别名
- H-2D[b] (H2-D1 产品)
- 别名
- H-2D antibody, H2-D antibody, histocompatibility 2, D region locus 1 antibody, H2-D1 antibody
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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