(3 references)-
- 抗原 See all FAS 抗体
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FAS antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Functional Studies (Func), Fluorescence Microscopy (FM)
- 品牌
- BD Pharmingen™
- 产品特性
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Reacts with a 45 kD type I membrane molecule also known as APO-1, or Fas antigen. CD95 belongs to the tumor necrosis factor receptor (TNF-R) family of proteins and is expressed on various cells, including activated T cells and B cells. The interaction of CD95, Fas antigen, with Fas ligand is one of the many mechanisms that lead to apoptosis or programmed cell death. The interaction of CD95 expressing target cells with Fas ligand on cytotoxic T cells induces an apoptotic signal leading to target cell death. It has been reported that apoptosis is the mechanism used by the immune system in clonal deletion of self-reactive T cells during embryological development. Jurkat cells treated for 6 hours with CD95 (EOS9.1) Jurkat cells treated for 6 hours with mouse IgM isotype control
BD Pharmingen™ Purified Mouse Anti-Human CD95 - Purified - Clone EOS9.1 - Isotype Mouse IgM, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- EOS9-1
- 亚型
- IgM kappa
- Top Product
- Discover our top product FAS Primary Antibody
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anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 150-250) antibody
FAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) antibodyFAS 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 4F8H6 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 87-109), (N-Term) antibodyFAS 适用: 大鼠, 小鼠 WB, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-172) antibodyFAS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-169) antibodyFAS 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 21-170) antibodyFAS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 26-96) antibodyFAS 适用: 人 FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal FAS-3112 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibodyFAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 5B4 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) antibodyFAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B6 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibodyFAS 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2G3 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing no preservative.
- 储存液
- Without preservative
- 注意事项
- This preparation contains no preservatives, thus it should be handled under aseptic conditions.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "The role of APO-1-mediated apoptosis in the immune system." in: Immunological reviews, Vol. 142, pp. 175-91, (1995) (PubMed).
: "The Fas death factor." in: Science (New York, N.Y.), Vol. 267, Issue 5203, pp. 1449-56, (1995) (PubMed).
: "Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity." in: The Journal of experimental medicine, Vol. 177, Issue 1, pp. 195-200, (1993) (PubMed).
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: "The role of APO-1-mediated apoptosis in the immune system." in: Immunological reviews, Vol. 142, pp. 175-91, (1995) (PubMed).
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- 抗原
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
- 别名
- CD95 (FAS 产品)
- 别名
- ALPS1A antibody, APO-1 antibody, APT1 antibody, CD95 antibody, FAS1 antibody, FASTM antibody, TNFRSF6 antibody, AI196731 antibody, APO1 antibody, TNFR6 antibody, Tnfrsf6 antibody, lpr antibody, Fas cell surface death receptor antibody, Fas (TNF receptor superfamily member 6) antibody, FAS antibody, Fas antibody, fas antibody
- 背景
- Synonyms: Fas/APO-1
- 途径
- p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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