(1 reference)-
- 抗原 See all CD51/CD61 (ITGAV/ITGB3) 抗体
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
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适用
- 人, 兔
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD51/CD61 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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Reacts with the integrin αvβ3 heterodimeric complex (CD51/CD61), which is expressed in high amounts on osteoclasts, endothelial cells, melanoma cells, and in very low amounts on platelets. This antibody has been reported to cross-react with chicken and rabbit, but not with rat, αvβ3. The integrin αvβ3, often referred to as the vitronectin receptor, binds several ligands in addition to vitronectin, and its binding to some ligands has been reported to be inhibited by the 23C6 mAb. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of M21 (melanoma) cells analyzed by flow cytometry
BD Pharmingen™ Purified Mouse Anti-Human CD51/CD61 - Purified - Clone 23C6 - Isotype Mouse IgG1, κ - Reactivity Hu, Rab - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- 23C6
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product ITGAV/ITGB3 Primary Antibody
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anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody
ITGAV/ITGB3 适用: 人, 小鼠, 大鼠 FACS, WB, IF (cc), IF (p), IHC (fro), ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody (FITC)ITGAV/ITGB3 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal BV3 FITC
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibodyITGAV/ITGB3 适用: 人, 小鸡, 兔 FACS, IHC, IHC (fro) 宿主: 小鼠 Monoclonal 23C6 unconjugated
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibodyITGAV/ITGB3 适用: 人, 小鸡 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal 23C6 unconjugated
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody (PE)ITGAV/ITGB3 适用: 人, 小鸡 FACS 宿主: 小鼠 Monoclonal 23C6 PE
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "Biochemical characterization of human osteoclast integrins. Osteoclasts express alpha v beta 3, alpha 2 beta 1, and alpha v beta 1 integrins." in: The Journal of biological chemistry, Vol. 268, Issue 22, pp. 16737-45, (1993) (PubMed).
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: "Biochemical characterization of human osteoclast integrins. Osteoclasts express alpha v beta 3, alpha 2 beta 1, and alpha v beta 1 integrins." in: The Journal of biological chemistry, Vol. 268, Issue 22, pp. 16737-45, (1993) (PubMed).
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- 抗原
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
- 别名
- CD51/CD61 (ITGAV/ITGB3 产品)
- 别名
- CD51 antibody, MSK8 antibody, VNRA antibody, VTNR antibody, integrin subunit alpha V antibody, ITGAV antibody
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