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Integrin alpha 1 抗体

ITGA1 适用: 小鼠, 大鼠 WB, FACS, IP, IHC (fro), BR, IHC (f) 宿主: Armenian Hamster Monoclonal Ha31-8 unconjugated
产品编号 ABIN2689296
发货至: 中国
  • 抗原 See all Integrin alpha 1 (ITGA1) 抗体
    Integrin alpha 1 (ITGA1)
    适用
    • 66
    • 33
    • 17
    • 4
    • 1
    小鼠, 大鼠
    宿主
    • 53
    • 15
    • 1
    • 1
    Armenian Hamster
    克隆类型
    • 58
    • 12
    单克隆
    标记
    • 33
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    This Integrin alpha 1 antibody is un-conjugated
    应用范围
    • 49
    • 23
    • 22
    • 14
    • 13
    • 13
    • 12
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
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    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    品牌
    BD Pharmingen™
    产品特性
    The Ha31/8 antibody reacts with the 180- kDa integrin α1 chain (CD49a), which is a transmembrane glycoprotein that non-covalently associates with the integrin β1 subunit (CD29) to form the α1β1 (complex known as VLA-1). VLA-1 has been reported to be expressed on activated T cells, monocytes, smooth muscle cells, and endothelial cells. It is a receptor for collagen and laminin. The Ha31/8 monoclonal antibody is specific for both rat1 and mouse CD49a. It has been reported that Ha31/8 antibody can block VLA-1-mediated binding of rat cells to collagen.

    BD Pharmingen™ Purified Hamster anti-rat/mouse CD49a - Purified - Clone Ha31/8 - Isotype Armenian Hamster IgG2, λ1 - 0.5 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Rat Emulsified Lewis Rat Glomeruli Cells
    克隆位点
    Ha31-8
    亚型
    IgG2 lambda
    Top Product
    Discover our top product ITGA1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Mendrick, Kelly, duMont, Sandstrom: "Glomerular epithelial and mesangial cells differentially modulate the binding specificities of VLA-1 and VLA-2." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 72, Issue 3, pp. 367-75, (1995) (PubMed).

    Miyake, Sakurai, Okumura, Yagita: "Identification of collagen and laminin receptor integrins on murine T lymphocytes." in: European journal of immunology, Vol. 24, Issue 9, pp. 2000-5, (1994) (PubMed).

    Hemler: "VLA proteins in the integrin family: structures, functions, and their role on leukocytes." in: Annual review of immunology, Vol. 8, pp. 365-400, (1990) (PubMed).

  • 抗原
    Integrin alpha 1 (ITGA1)
    别名
    CD49a (ITGA1 产品)
    别名
    CD49A antibody, E130012M19Rik antibody, Vla1 antibody, CD49a antibody, VLA1 antibody, integrin alpha 1 antibody, integrin subunit alpha 1 antibody, Itga1 antibody, ITGA1 antibody
    背景
    Synonyms: Integrin α1 chain
    途径
    EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex
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