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CD47 抗体

CD47 适用: 人 FACS, IHC (fro) 宿主: 小鼠 Monoclonal B6H12 unconjugated
产品编号 ABIN2689294
发货至: 中国
  • 抗原 See all CD47 抗体
    CD47
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD47 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    品牌
    BD Pharmingen™
    产品特性
    Reacts with a 42-52 kD N-linked glycan protein. CD47 antigen, also known as integrin-associated protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells. B6H12 antibody is capable of blocking phagocytosis of microparticles by peripheral blood granulocytes. It has also been reported to induce proliferation of CD3-activated T cells. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed by flow cytometry

    BD Pharmingen™ Purified Mouse Anti-Human CD47 - Purified - Clone B6H12 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    B6H12
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD47 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Lindberg, Lublin, Telen, Veile, Miller, Donis-Keller, Brown: "Rh-related antigen CD47 is the signal-transducer integrin-associated protein." in: The Journal of biological chemistry, Vol. 269, Issue 3, pp. 1567-70, (1994) (PubMed).

    Gresham, Goodwin, Allen, Anderson, Brown: "A novel member of the integrin receptor family mediates Arg-Gly-Asp-stimulated neutrophil phagocytosis." in: The Journal of cell biology, Vol. 108, Issue 5, pp. 1935-43, (1989) (PubMed).

  • 抗原
    CD47
    别名
    CD47 (CD47 产品)
    别名
    IAP antibody, MER6 antibody, OA3 antibody, 9130415E20Rik antibody, AA407862 antibody, AI848868 antibody, AW108519 antibody, B430305P08Rik antibody, Itgp antibody, CD47/IAP antibody, alkaline phosphatase, intestinal antibody, CD47 molecule antibody, CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antibody, Cd47 molecule antibody, ALPI antibody, CD47 antibody, Cd47 antibody
    背景
    Synonyms: IAP
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