-
- 抗原 See all IGF1R 抗体
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This IGF1R antibody is un-conjugated
-
应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
-
Reacts with human insulin-like growth factor-I (IGF-I) receptor. IGF-I receptor is a glycoprotein complex composed of two extracellular α subunits and two transmembrane β subunits. The transmembrane subunits play a role in tyrosine phosphorylation of several intracellular signaling proteins. IGF-I receptor is structurally and functionally similar to insulin receptor and is expressed on a variety of human hematopoietic and non-hematopoietic cells. 3B7 antibody does not cross react with human insulin receptor, it stimulates IGF-I and IGF-II induced cell growth and activates autophosphorylation of the IGF-I receptor β subunit. Profile of Jurkat Cells analyzed on a FACScan with Biotin Goat anti-mouse Ig (Cat. No. 553999) as 2nd step, and with SAV-PE (Cat. No. 554061) as 3rd step. CD221 expression (filled) and isotype control (dash lines)
BD Pharmingen™ Purified Mouse Anti-Human CD221 - Purified - Clone 3B7 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- 3B7
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product IGF1R Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
-
-
Differential expression of type I insulin-like growth factor receptors in different stages of human T cells." in: European journal of immunology, Vol. 25, Issue 4, pp. 931-5, (1995) (PubMed).
: "Growth-stimulatory monoclonal antibodies against human insulin-like growth factor I receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 12, pp. 5356-60, (1992) (PubMed).
: "
-
Differential expression of type I insulin-like growth factor receptors in different stages of human T cells." in: European journal of immunology, Vol. 25, Issue 4, pp. 931-5, (1995) (PubMed).
-
- 抗原
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
- 别名
- CD221 (IGF1R 产品)
- 别名
- CMT2N antibody, CD221 antibody, IGFIR antibody, IGFR antibody, JTK13 antibody, IGFIRC antibody, IGFR1 antibody, IGF-1R antibody, IGF1R antibody, DKFZp469I0618 antibody, igf-1r antibody, xIGF-1R antibody, xIGFR antibody, xigf1r antibody, A330103N21Rik antibody, D930020L01 antibody, hyft antibody, igf-ir antibody, IGF-IR antibody, IGF-IRb antibody, wu:fb03h06 antibody, IGF-IRa antibody, sb:eu1090 antibody, wu:fi20b10 antibody, alanyl-tRNA synthetase antibody, insulin like growth factor 1 receptor antibody, insulin-like growth factor 1 receptor antibody, insulin-like growth factor 1 antibody, insulin-like growth factor I receptor antibody, insulin like growth factor 1 receptor S homeolog antibody, insulin-like growth factor 1b receptor antibody, insulin-like growth factor 1a receptor antibody, AARS antibody, IGF1R antibody, Igf1r antibody, igf1r antibody, Igf1 antibody, LOC780503 antibody, LOC100136427 antibody, igf1r.S antibody, igf1rb antibody, igf1ra antibody
- 背景
- Synonyms: IGF-I receptor
- 途径
- RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
-