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CD200 抗体

CD200 适用: 人 FACS 宿主: 小鼠 Monoclonal MRC OX unconjugated
产品编号 ABIN2689078
发货至: 中国
  • 抗原 See all CD200 抗体
    CD200
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD200 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    品牌
    BD Pharmingen™
    产品特性
    Reacts with a 40-45 kDa membrane glycoprotein also referred to as OX2. CD200 is a member of the immunoglobulin superfamily of proteins. It contains two Ig domains, a single transmembrane region and a short cytoplasmic tail. CD200 is expressed on resting and PMA-activated T- and B-cells, but not on NK cells, monocytes, granulocytes, or platelets. It has been found on a subset of CD34+ progenitor cells. Interaction of CD200 with its receptor on macrophages induces a downregulation of macrophage activity in a variety of tissues, suggesting a regulatory function. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of anti-CD200, clone MRC OX-104, staining on peripheral blood lymphocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.

    BD Pharmingen™ Purified Mouse Anti-Human CD200 - Purified - Clone MRC OX-104 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    MRC OX
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD200 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Wright, Jones, Puklavec, Brown, Barclay: "The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans." in: Immunology, Vol. 102, Issue 2, pp. 173-9, (2001) (PubMed).

    Hoek, Ruuls, Murphy, Wright, Goddard, Zurawski, Blom, Homola, Streit, Brown, Barclay, Sedgwick: "Down-regulation of the macrophage lineage through interaction with OX2 (CD200)." in: Science (New York, N.Y.), Vol. 290, Issue 5497, pp. 1768-71, (2000) (PubMed).

    Wright, Puklavec, Willis, Hoek, Sedgwick, Brown, Barclay: "Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function." in: Immunity, Vol. 13, Issue 2, pp. 233-42, (2000) (PubMed).

  • 抗原
    CD200
    别名
    CD200 (CD200 产品)
    别名
    MOX1 antibody, MOX2 antibody, MRC antibody, OX-2 antibody, CD200 antibody, Cspmo2 antibody, MRCOX2 antibody, Mox2 antibody, DKFZp459C0716 antibody, OX2 antibody, CD200 molecule antibody, Cd200 molecule antibody, CD200 antigen antibody, CD200 antibody, Cd200 antibody
    背景
    Synonyms: OX2
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