(4 references)-
- 抗原 See all IFNGR1 抗体
- IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This IFNGR1 antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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The GR20 antibody reacts with CD119, the α chain of the interferon γ (IFN-γ) receptor. This receptor is expressed by mouse leukocytes, endothelial, and epithelial cells, but not by mature erythrocytes. GR20 mAb recognizes an epitope (susceptible to certain fixatives) in the ligand-binding site of the receptor. It can block the binding of mouse IFN-γ, therefore, it can inhibit IFN-γ .mediated effects including the activation of mouse macrophages for tumor cell killing. IFN-γ has been reported to induce the expression of Ly-6A/E antigen on cell lines and normal B lymphocytes, and the GR20 antibody is capable of inhibiting the IFN-γ.induced expression of Ly-6A/E on the mouse B lymphoma line A20. The binding of the GR20 antibody to CD119 is inhibited by IFN-γ. This antibody reportedly does not have any agonist effect.
BD Pharmingen™ Biotin Rat Anti-Mouse CD119 - Biotin - Clone GR20 - Isotype Rat IgG2a, κ - Reactivity Ms - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- BALB/c mouse monomyelocytic cell line WEHI-3
- 克隆位点
- GR20
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product IFNGR1 Primary Antibody
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anti-Interferon gamma Receptor 1 (IFNGR1) (AA 270-489) antibody
IFNGR1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma Receptor 1 (IFNGR1) (AA 18-245) antibodyIFNGR1 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 5H1C9 unconjugated
anti-Interferon gamma Receptor 1 (IFNGR1) (AA 1-489) antibodyIFNGR1 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon gamma Receptor 1 (IFNGR1) antibodyKO Validated IFNGR1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma Receptor 1 (IFNGR1) (C-Term) antibodyIFNGR1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma Receptor 1 (IFNGR1) (AA 431-480) antibodyIFNGR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma Receptor 1 (IFNGR1) (AA 18-245) antibodyIFNGR1 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma Receptor 1 (IFNGR1) (AA 1-489) antibodyIFNGR1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon gamma Receptor 1 (IFNGR1) (AA 181-193) antibodyVerified IFNGR1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interferon gamma Receptor 1 (IFNGR1) antibodyIFNGR1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "Characterization and use of monoclonal and polyclonal antibodies against the mouse interferon-gamma receptor." in: Journal of leukocyte biology, Vol. 51, Issue 5, pp. 507-16, (1992) (PubMed).
: "Affinity purification, peptide analysis, and cDNA sequence of the mouse interferon gamma receptor." in: The Journal of biological chemistry, Vol. 265, Issue 7, pp. 4064-71, (1990) (PubMed).
: "Regulation of B lymphocyte responses to IL-4 and IFN-gamma by activation through Ly-6A/E molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 6, pp. 2197-204, (1990) (PubMed).
: "Purification and partial characterization of a receptor protein for mouse interferon gamma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 17, pp. 6282-6, (1988) (PubMed).
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: "Characterization and use of monoclonal and polyclonal antibodies against the mouse interferon-gamma receptor." in: Journal of leukocyte biology, Vol. 51, Issue 5, pp. 507-16, (1992) (PubMed).
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- 抗原
- IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))
- 别名
- CD119 (IFNGR1 产品)
- 别名
- CD119 antibody, IFNGR antibody, IFN-gammaR antibody, Ifgr antibody, Ifngr antibody, Nktar antibody, IFNGR1 antibody, MGC129098 antibody, ifngr1 antibody, MGC194858 antibody, MGC194873 antibody, zgc:194858 antibody, cd119 antibody, ifngr antibody, DKFZp469K1232 antibody, interferon gamma receptor 1 antibody, cytokine receptor family member B17 antibody, IFNGR1 antibody, Ifngr1 antibody, crfb17 antibody, ifngr1 antibody
- 背景
- Synonyms: IFN-γ receptor α chain
- 途径
- Interferon-gamma Pathway
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