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NF-kB p65 抗体 (AA 526-539)

Name: NF-kB p65 抗体 (AA 526-539)
SKU: ABIN2668795
Availability: OutOfStock

There is 1 publication for this product available. The 小鼠单克隆 anti-NF-kB p65 antibody is suitable to detect NF-kB p65 in samples from 人和小鼠. It has been validated for WB 和 ChIP.

NFκB p65 mAb tested by Western blot. (NF-kB p65 抗体 (AA 526-539))

1 image

(1 reference)

产品编号 ABIN2668795

发货至: 中国

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Quick Overview for NF-kB p65 抗体 (AA 526-539) (ABIN2668795)

抗原

See all NF-kB p65 (NFkBP65) 抗体

NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

适用

人, 小鼠

宿主

小鼠

克隆类型

单克隆

标记

This NF-kB p65 antibody is un-conjugated

应用范围

Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

克隆位点

112A1021

Discover our top product NFkBP65 Primary Antibody

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AA 526-539

原理

NFkB p65 antibody (mAb) (Clone 112A1021)

纯化方法

Affinity Purified

免疫原

This NFkB p65 antibody was raised against a synthetic peptide corresponding to amino acid residues 526-539 of human NFkB p65.

亚型

IgG1
anti-Nuclear Factor-kB p65 (NFkBP65) (AA 51-100) antibody
NFkBP65 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 兔, 小鸡 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Factor-kB p65 (NFkBP65) (pSer536) antibody
NFkBP65 适用: 人, 小鼠, 大鼠, Cow, 小鸡 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Factor-kB p65 (NFkBP65) (pSer536) antibody
NFkBP65 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Factor-kB p65 (NFkBP65) antibody
NFkBP65 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Factor-kB p65 (NFkBP65) (Center) antibody
NFkBP65 适用: 人, 小鼠 WB, IF, IHC (p), ICC, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Factor-kB p65 (NFkBP65) (AA 19-306) antibody
NFkBP65 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Factor-kB p65 (NFkBP65) (pThr435) antibody
NFkBP65 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Factor-kB p65 (NFkBP65) (pSer281) antibody
NFkBP65 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nuclear Factor-kB p65 (NFkBP65) (C-Term) antibody
NFkBP65 适用: 人, 小鼠 WB, IHC, IP, ICC 宿主: 兔 Monoclonal BLR361N unconjugated Recombinant Antibody

anti-Nuclear Factor-kB p65 (NFkBP65) (AA 10-37), (N-Term) antibody
NFkBP65 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB20786 unconjugated

应用备注

WB: 2 - 5 μg/mL dilution For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1 % Tween 20 to all blocking solutions may also reduce background. Individual optimization may be required.

限制

仅限研究用
浓度

0.5 μg/μL

缓冲液

PBS containing 0.05 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

储存条件

4 °C,-20 °C

储存方法

Some products may be shipped at room temperature. This will not affect their stability or performance. Store at 4°C for short term. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

有效期

24 months
Sun, Alkhoury, Wang, Foster, Radecke, Tam, Edwards, Facciotti, Armstrong, Knowlton, Newman, Passerini, Simon: "IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high-fat meal." in: Circulation research, Vol. 111, Issue 8, pp. 1054-64, (2012) (PubMed).
抗原

NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

别名

NFkappaB p65

背景

NFkB p65 (Nuclear factor NF-kappa-B p65 subunit also known as NFkB p65 or RelA) is a member of the Rel family of transcription factors that are involved in processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. The Rel family includes c-Rel, RelA (NFkB p65, NFkB3) and RelB (I-Rel). Rel proteins form dimers with the NFkB p50 (proteolytically processed from p105/NFkB1) and p52 (proteolytically processed from p100/NFkB2) members of the NFkB family that bind DNA and activate transcription. The NFkB p65/p50 heterodimer is the most abundant form of NFkB. NFkB signaling is negatively regulated by the sequestration of the NFkB complex in the cytoplasm by its association with the IkB family of inhibitory proteins. The IkB Kinase (IKK) complex is the key enzyme involved in the activation and translocation of NFkB. The IKK complex is composed of two catalytic subunits (IKKa and IKKb) and a regulatory subunit (IKKg). Upon its activation, the IKK complex phosphorylates IkB proteins (IkBa, IkBa phospho Ser32, 36), which marks them for ubiquitination and degradation. This enables the NFkB complex to translocate to the nucleus where it regulates transcription by binding to DNA.

分子量

65 kDa

基因ID

5970

NCBI登录号

NP_068810

途径

NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins