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Histone 3 抗体 (H3K122me1)

There is 1 publication for this product available. The 兔 多克隆 anti-Histone 3 antibody is suitable to detect Histone 3 in samples from 人. It has been validated for WB 和 DB.
产品编号 ABIN2668462
发货至: 中国
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Quick Overview for Histone 3 抗体 (H3K122me1) (ABIN2668462)

抗原

See all Histone 3 (H3) 抗体
Histone 3 (H3) (Histone H3 (H3))

适用

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人

宿主

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兔

克隆类型

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多克隆

标记

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This Histone 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Dot Blot (DB)
  • 抗原表位

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    H3K122me1

    原理

    Histone H3K122me1 antibody (pAb)

    纯化方法

    Affinity Purified

    免疫原

    This Histone H3 monomethyl Lys122 antibody was raised against a peptide containing monomethyl-lysine 122 of human histone H3.

    亚型

    IgG
  • 应用备注

    WB: 1:250 - 1:1,000 dilution

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • Ivanauskiene, Delbarre, McGhie, Küntziger, Wong, Collas: "The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity." in: Genome research, Vol. 24, Issue 10, pp. 1584-94, (2014) (PubMed).

  • 抗原

    Histone 3 (H3) (Histone H3 (H3))

    别名

    Histone H3

    背景

    Histone H3 is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, these modifications play a major role in regulating gene expression. The methylation of histones can occur on two different residues: arginine or lysine. Histone methylation can be associated with transcriptional activation or repression, depending on the methylated residue.

    分子量

    17 kDa

    基因ID

    3020

    NCBI登录号

    NP_003522
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