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LEF1 抗体
LEF1
适用: 人
BCA
宿主: 小鼠
Monoclonal
15H5A18
unconjugated
LEF1抗体详情
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抗原
See all LEF1 抗体
LEF1
(Lymphoid Enhancer-Binding Factor 1 (LEF1))
适用
All reactivities for LEF1 抗体
人
宿主
All hosts for LEF1 抗体
小鼠
克隆类型
All clonalities for LEF1 抗体
单克隆
标记
All conjugates for LEF1 抗体
This LEF1 antibody is un-conjugated
应用范围
All applications for LEF1 抗体
Biochemical Assay (BCA)
克隆位点
15H5A18
亚型
IgG1 kappa
Top Product
Discover our top product LEF1 Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
phosphate-buffered solution, pH 7.2, containing 0.05 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
Upon receipt, store undiluted between 2°C and 8°C.
LEF1目标详情
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抗原
LEF1
(Lymphoid Enhancer-Binding Factor 1 (LEF1))
别名
LEF1 (LEF1 产品 )
别名
LEF1 antibody, 3000002B05 antibody, AI451430 antibody, Lef-1 antibody, LEF-1 antibody, TCF10 antibody, TCF1ALPHA antibody, TCF7L3 antibody, lymphoid enhancer binding factor 1 antibody, lymphoid enhancer-binding factor 1 antibody, lymphoid enhancer factor XLEF-1B antibody, LEF1 antibody, lef1 antibody, Lef1 antibody
背景
Lymphoid Enhancing Factor 1 (LEF1) is a transcription factor belonging to the TCF/LEF family. LEF1 was first identified as a protein binding to TCR- α enhancer and upregulates expression of T-cell antigen receptor α chain. LEF1 is involved in Wnt signaling pathways as a ubiquitous regulator. During Wnt signaling, translocation of β-catenin from the cytosol to the nucleus results in elevation of transcriptional activity of LEF1, which subsequently regulates multiple downstream genes.
途径
WNT signaling , Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Hormone Metabolic Process , Nuclear Hormone Receptor Binding , Chromatin Binding
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