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BID 抗体

BID 适用: 人 FACS 宿主: 大鼠 Monoclonal 1H11 unconjugated
产品编号 ABIN2666317
发货至: 中国
  • 抗原 See all BID 抗体
    BID (BH3 Interacting Domain Death Agonist (BID))
    适用
    • 122
    • 66
    • 30
    • 2
    • 2
    • 1
    宿主
    • 133
    • 18
    • 2
    • 2
    大鼠
    克隆类型
    • 125
    • 29
    单克隆
    标记
    • 84
    • 16
    • 12
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This BID antibody is un-conjugated
    应用范围
    • 137
    • 57
    • 51
    • 37
    • 28
    • 28
    • 26
    • 16
    • 11
    • 11
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    1H11
    亚型
    IgG1
    Top Product
    Discover our top product BID Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    phosphate-buffered solution, pH 7.2, 0.09 % Sodium azide.
    储存条件
    4 °C
    储存方法
    Upon receipt, store undiluted between 2°C and 8°C.
  • 抗原
    BID (BH3 Interacting Domain Death Agonist (BID))
    别名
    BID (BID 产品)
    别名
    FP497 antibody, 2700049M22Rik antibody, AI875481 antibody, AU022477 antibody, BID antibody, bid antibody, si:ch211-238n5.6 antibody, fp497 antibody, xbid antibody, DKFZp469E066 antibody, BH3 interacting domain death agonist antibody, BH3 interacting domain death agonist S homeolog antibody, BID antibody, Bid antibody, bida antibody, bid.S antibody, bid antibody
    背景
    BID, a BH3 interacting domain death agonist is a member of the Bcl-2/Bcl-xL family. BID can form a heterodimer with either agonist BAX or antagonist Bcl-2. It is a mediator of mitochondrial damage induced by Caspase-8 (CASP8). After the cleavage by CASP8, the COOH-terminal part translocates to mitochondria and induces cytochrome c release, which in turn activates downstream caspases. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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