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KAP1 抗体

The 小鼠 单克隆 anti-KAP1 antibody (Clone 20A1) (ABIN2666087) specifically detects KAP1 in BCA. The antibody is reactive with 人 samples.
产品编号 ABIN2666087
发货至: 中国
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Quick Overview for KAP1 抗体 (ABIN2666087)

抗原

See all KAP1 (TRIM28) 抗体
KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This KAP1 antibody is un-conjugated

应用范围

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Biochemical Assay (BCA)

克隆位点

20A1
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Upon receipt, store between 2°C and 8°C.
  • 抗原

    KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

    别名

    TIF1beta KAP-1

    背景

    TIFβ (transcription intermediary factor 1-beta) is an 88 kD member of the tripartite motif family. This protein contains three zinc binding domains, a RING domain, a B-box type 1 and type 2 domain, and a coiled-coil region. TIFβ is found in the nucleus and associates with specific chromatin regions. This protein forms a complex with KRAB-domain transcription factors and recruits setdbl to histone 3 to increase KRAB-mediated transcriptional repression. TIF1β has been reported to interact with setdbl and cbx3 proteins. Studies using knockout mice reveal the important function of TIF1β in regulating genomic imprinting, T cell activation, and T cell tolerance.

    途径

    Hedgehog Signaling, Positive Regulation of Response to DNA Damage Stimulus
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