Histone 3 抗体 (pSer28)
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Quick Overview for Histone 3 抗体 (pSer28) (ABIN2666077)
抗原
See all Histone 3 (H3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer28
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纯化方法
- The antibody was purified by affinity chromatography.
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免疫原
- AA 23-35 of human histone H3.
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亚型
- IgG2a kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide. Final antibody concentration is 0.5 mg/mL.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Upon receipt, store between 2°C and 8°C.
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- Histone 3 (H3) (Histone H3 (H3))
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别名
- Histone H3
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背景
- H3 is a core component of the nucleosome that serves to wrap and compact DNA into chromatin. Histones therefore, limit the accessibility of DNA, providing mechanisms for transcription regulation, DNA repair and replication and chromosomal stability. During mitosis, H3 is phosphorylated at serine 28.This phosphorylation coincides with chromosome condensation initiated at prophase and disappears at late anaphase. H3 has been demonstrated to be phosphorylated by the action of MLTK-α (mixed linage kinase-like mitogen activated protein triple kinase α) in response to ultraviolet B light and epidermal growth factor, as well as Aurora-B during mitosis.
抗原
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