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Histone 3 抗体 (pSer28)

The 大鼠 单克隆 anti-Histone 3 antibody is suitable to detect Histone 3 in samples from 人. It has been validated for ICFC.
产品编号 ABIN2666077
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Histone 3 抗体 (pSer28) (ABIN2666077)

抗原

See all Histone 3 (H3) 抗体
Histone 3 (H3) (Histone H3 (H3))

适用

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人

宿主

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大鼠

克隆类型

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单克隆

标记

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This Histone 3 antibody is un-conjugated

应用范围

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Intracellular Flow Cytometry (ICFC)

克隆位点

HTA28
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    pSer28

    纯化方法

    The antibody was purified by affinity chromatography.

    免疫原

    AA 23-35 of human histone H3.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide. Final antibody concentration is 0.5 mg/mL.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Upon receipt, store between 2°C and 8°C.
  • 抗原

    Histone 3 (H3) (Histone H3 (H3))

    别名

    Histone H3

    背景

    H3 is a core component of the nucleosome that serves to wrap and compact DNA into chromatin. Histones therefore, limit the accessibility of DNA, providing mechanisms for transcription regulation, DNA repair and replication and chromosomal stability. During mitosis, H3 is phosphorylated at serine 28.This phosphorylation coincides with chromosome condensation initiated at prophase and disappears at late anaphase. H3 has been demonstrated to be phosphorylated by the action of MLTK-α (mixed linage kinase-like mitogen activated protein triple kinase α) in response to ultraviolet B light and epidermal growth factor, as well as Aurora-B during mitosis.
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