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DDX3X 抗体

DDX3X 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 15D1B11 unconjugated
产品编号 ABIN2664926
发货至: 中国
  • 抗原 See all DDX3X 抗体
    DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))
    适用
    • 102
    • 41
    • 32
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 94
    • 8
    小鼠
    克隆类型
    • 94
    • 7
    单克隆
    标记
    • 58
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DDX3X antibody is un-conjugated
    应用范围
    • 70
    • 38
    • 33
    • 26
    • 26
    • 17
    • 16
    • 13
    • 11
    • 6
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    15D1B11
    亚型
    IgG1 kappa
    Top Product
    Discover our top product DDX3X Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))
    别名
    DDX3X (DDX3X 产品)
    别名
    DBX antibody, DDX14 antibody, DDX3 antibody, HLP2 antibody, D1Pas1-rs2 antibody, Ddx3 antibody, Fin14 antibody, An3 antibody, pl10 antibody, DDX3X antibody, DEAD-box helicase 3, X-linked antibody, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked antibody, DEAD-box helicase 3, X-linked L homeolog antibody, DDX3X antibody, Ddx3x antibody, ddx3x.L antibody, ddx3x antibody
    背景
    DDX3X belongs to the DEAD (Asp-Glu-Ala-Asp)-box protein family of RNA helicases, involved in the alteration of RNA secondary structure required for transcription, mRNA processing, and translation initiation. DDX3X is an essential host factor during virus infection. DDX3X serves as the cellular target of Hepatitis C virus (HCV) core protein, and also facilitates nuclear export of immature HIV RNA. The RNA helicase activity of DDX3X is required for the replication of both HCV and HIV. DDX3X is implied to act as a viral RNA sensor, mediating antiviral innate immune signaling. DDX3 participates in IκB kinase ε (IKKε) and TANK-binding kinase 1 (TBK1) dependent IRF3 activation, leading to the production of Type I interferon. DDX3X was also proposed to have antiapoptotic functions and participate in tumorigenesis.
    途径
    Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly
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