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C-Type Lectin Domain Family 1, Member B (CLEC1B) 抗体

CLEC1B 适用: 小鼠 FACS, IF 宿主: 大鼠 Monoclonal 17D9-CLEC2 unconjugated
产品编号 ABIN2664892
发货至: 中国
  • 抗原 See all C-Type Lectin Domain Family 1, Member B (CLEC1B) 抗体
    C-Type Lectin Domain Family 1, Member B (CLEC1B)
    适用
    • 40
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    小鼠
    宿主
    • 26
    • 13
    • 3
    • 1
    大鼠
    克隆类型
    • 29
    • 14
    单克隆
    标记
    • 21
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    • 1
    • 1
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    非结合性
    应用范围
    • 25
    • 17
    • 10
    • 4
    • 4
    • 4
    • 2
    Flow Cytometry (FACS), Immunofluorescence (IF)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    17D9-CLEC2
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CLEC1B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    C-Type Lectin Domain Family 1, Member B (CLEC1B)
    别名
    CLEC2 (CLEC1B 产品)
    别名
    1810061I13Rik antibody, CLEC2 antibody, CLEC2B antibody, PRO1384 antibody, QDED721 antibody, Clec-2 antibody, Clec2 antibody, CLEC1B antibody, RGD1563517 antibody, CLEC9A antibody, C-type lectin domain family 1 member B antibody, C-type lectin domain family 1, member b antibody, C-type lectin domain family 1, member B antibody, CLEC1B antibody, Clec1b antibody
    物质类
    Viral Protein
    背景
    CLEC-2, also known as CLEC1B and CLEC1B1, is C-type lectin-like receptor with a single cytoplasmic YXXL sequence known as a hem-immunoreceptor tyrosine-based activation motif (hemITAM). CLEC-2 is highly expressed on resting platelets and megakaryocytes and at a lower levels on several hematopoietic cells including monocytes, macrophages, dendritic cells, and granulocytes. The first ligand that was identified for CLEC-2 was the snake venom toxin rhodocytin, podoplanin has also been identified as an endogenous ligand for CLEC-2. Exposure of platelets to rhodocytin leads tyrosine phosphorylation of the ITAM-like motif and Syk-dependent platelet activation. CLEC-2 also functions as an activation receptor on monoyctes and neutrophils to induce phagocytosis and proinflammatory cytokine production.
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