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Caspase 1 抗体

This anti-Caspase 1 antibody is a 大鼠 单克隆 antibody detecting Caspase 1 in FACS. Suitable for 小鼠.
产品编号 ABIN2664090
发货至: 中国

Quick Overview for Caspase 1 抗体 (ABIN2664090)

抗原

See all Caspase 1 (CASP1) 抗体
Caspase 1 (CASP1)

适用

  • 109
  • 39
  • 35
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
小鼠

宿主

  • 128
  • 12
  • 3
  • 1
大鼠

克隆类型

  • 117
  • 27
单克隆

标记

  • 97
  • 23
  • 9
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This Caspase 1 antibody is un-conjugated

应用范围

  • 116
  • 72
  • 47
  • 32
  • 24
  • 21
  • 20
  • 5
  • 3
  • 3
  • 3
  • 1
Flow Cytometry (FACS)

克隆位点

5B10
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    Caspase 1 (CASP1)

    别名

    Caspase-1

    背景

    Caspase -1 plays a vital role in cleaving the inactive procytokine pro-IL-1 beta to generate the active 17 kd mature form of IL-1beta, a key mediator of inflammation. Active caspase-1 (ICE) is derived a single proenzyme of 45 Kd. An active ICE comprises two subunits of P20 and two subunits of P10 after removal a large amino-terminal pro-domain and a small linker peptide. Caspase-1 is reported to be involved in CD95- mediated apoptosis. Four alternatively spliced variants of caspase-1 have been reported, with mw ranging from 30-48 kd.

    途径

    Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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