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TCR gamma/delta 抗体 (PE)

TCR gamma/delta 适用: 小鼠 FACS, IHC, IF 宿主: 仓鼠 Monoclonal UC7-13D5 PE
产品编号 ABIN2663899
发货至: 中国
  • 抗原 See all TCR gamma/delta products
    TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))
    适用
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    小鼠
    宿主
    • 34
    • 12
    • 12
    • 2
    仓鼠
    克隆类型
    • 60
    单克隆
    标记
    • 19
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    • 1
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    This TCR gamma/delta antibody is conjugated to PE
    应用范围
    • 60
    • 17
    • 16
    • 11
    • 10
    • 3
    • 3
    • 2
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    UC7-13D5
    亚型
    IgG
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))
    别名
    TCR gamma/delta (TCR gamma/delta 产品)
    背景
    T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR γ/δ associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR γ/δ have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-γ/δ-bearing T cells in vitro, and to deplete peripheral TCR-γ/δ-bearing T cells in vivo.
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